The evolution of microorganisms often involves changes of unclear relevance, such as
transient phenotypes and sequential development of multiple adaptive mutations in hotspot …

We report here the transcriptome analyses of highly expressed genes that are subject to
catabolite repression or activation mediated by the cyclic AMP receptor protein (Crp). The …

In Gram-positive bacteria, the catabolite control protein A (CcpA) functions as the master
transcriptional regulator of carbon catabolite repression/regulation (CCR). To effect CCR …

Certain bacteria are able to conserve energy via the reductive dehalogenation of halo‐
organic compounds in a respiration‐type metabolism. The transcriptional regulator CprK …

The Crc protein is a translational repressor that recognizes a specific target at some mRNAs,
controlling catabolite repression and co‐ordinating carbon metabolism in pseudomonads. In …

Two major transcriptional regulators of carbon metabolism in bacteria are Cra and CRP.
CRP is considered to be the main mediator of catabolite repression. Unlike for CRP, in vivo …

The carbon catabolite control protein A (CcpA) senses the physiological state of the cell by
binding several effectors and responds with differential regulation of many genes in Bacilli …

Transcriptional regulation is the key to ensuring that proteins are expressed at the proper
time and the proper amount. In Escherichia coli, the transcription factor cAMP receptor …

How do hierarchical gene regulation networks evolve in bacteria? Nucleoid-associated
proteins (NAPs) influence the overall structure of bacterial genomes, sigma factors and …

Carbon catabolite repression (CCR) by transcriptional regulators follows different
mechanisms in gram-positive and gram-negative bacteria. In gram-positive bacteria, CcpA …