ABSTRACT The cytochrome P450 (P450) field came out of interest in the metabolism of
drugs, carcinogens, and steroids, which remain major focal points. Over the years we have …

Abstract The cytochrome P450 (P450) enzymes first attracted interest because of their
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …

The field of cytochrome P450 (P450) research has developed considerably over the past 20
years, and many important papers on the roles of P450s in chemical toxicology have …

Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a
review that summarizes the current state of research in the field of drug metabolism. The …

The development of the cytochrome P450 (P450) field has been remarkable in the areas of
pharmacology and toxicology, particularly in drug development. Today it is possible to use …

Many members of the superfamily of hemeproteins, known as cytochrome P450 (P450 or
CYP), are currently described in the literature (over 2000 at the date of this writing)[see …

Cytochromes P450: Metabolic and Toxicological Aspects examines cytochrome P450
proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals …

Abstract Cytochrome P450 (P450) enzymes include a family of related enzymes that are
involved in metabolism of vitamins, steroids, fatty acids, and other chemicals. This review …

During half a century, cytochrome P450 in its original uniqueness as an optically" wrong"
cytochrome has attracted many investigators, who have contributed to the unveiling of a …

Cytochrome P450 isoenzymes are pivotal in drug clearance. Part 1 of this two-part review,
published in the October issue of Drug Discovery Today, described the active site …