Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive
resource for anyone looking to understand how polymeric materials can be applied to …

Endocytic uptake and subcellular trafficking of a large array of HPMA (N-(2-hydroxypropyl)
methacrylamide) based copolymers possessing positively or negatively charged residues …

Copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) are prototypic and well-
characterized polymeric drug carriers that have been broadly implemented in the delivery of …

Water-soluble copolymers based on N-(2-hydroxypropyl) methacrylamide (HPMA) are
investigated as potential carriers of anticancer drugs. For application of such compounds in …

Macromolecular conjugation is a useful method for controlling the pharmacokinetic profiles
of small drugs, proteins, oligonucleotides and genes. Site-specific drug delivery can be …

In this paper we describe the synthesis, physicochemical characteristics and data on the
biological activity of polymer prodrugs based on the anticancer drugs paclitaxel (PTX) and …

Copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) are prototypic and well-
characterized polymeric drug carriers that have been broadly implemented in the delivery of …

The use of water-soluble polymeric conjugates as drug carriers offers several possible
advantages. These advantages include:(1) improved drug pharmacokinetics;(2) decreased …

The increasing complexity of biological molecules being developed for medical applications
requires more sophisticated carrier materials to take these potent but delicate therapeutics to …

Due to the high cost and uncertain success of new drug development, tremendous effort is
devoted to increasing the efficacy of established anti-cancer drugs. Development of polymer …