[HTML][HTML] Early retinal inflammatory biomarkers in the middle cerebral artery occlusion model of ischemic stroke
Purpose The transient middle cerebral artery occlusion (MCAO) model of stroke is one of the
most commonly used models to study focal cerebral ischemia. This procedure also results in …
most commonly used models to study focal cerebral ischemia. This procedure also results in …
Changes in macrophage-like cells characterized by en face optical coherence tomography after retinal stroke
Y Zeng, F Wen, L Mi, Y Ji, X Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Purpose The retina could serve as a window of neuroinflammation, but the in vivo changes
in macrophage-like cell (MLC), such as microglia, in acute ischemic retinal stroke remain …
in macrophage-like cell (MLC), such as microglia, in acute ischemic retinal stroke remain …
Eyeballing stroke: blood flow alterations in the eye and visual impairments following transient middle cerebral artery occlusion in adult rats
J Lee, V Castelli, B Bonsack… - Cell …, 2020 - journals.sagepub.com
Middle cerebral artery occlusion in rodents remains a widely used model of ischemic stroke.
Recently, we reported the occurrence of retinal ischemia in animals subjected to middle …
Recently, we reported the occurrence of retinal ischemia in animals subjected to middle …
Neurosurgical modeling of retinal ischemia–reperfusion injury
Background A reliable model of ischemia–reperfusion is required to evaluate the efficacy
and safety of neuroprotective therapies for stroke. We present a novel reproducible …
and safety of neuroprotective therapies for stroke. We present a novel reproducible …
[HTML][HTML] A mouse model of retinal hypoperfusion injury induced by unilateral common carotid artery occlusion
Retina, one of the highest oxygen demanding tissues, is vulnerable to vascular
insufficiencies, and various ocular vascular disorders can cause chronic retinal ischemia. To …
insufficiencies, and various ocular vascular disorders can cause chronic retinal ischemia. To …
[HTML][HTML] Optimization of an Ischemic Retinopathy Mouse Model and the Consequences of Hypoxia in a Time-Dependent Manner
I Bosnyak, N Farkas, D Molitor, B Meresz… - International Journal of …, 2024 - mdpi.com
The retina is one of the highest metabolically active tissues with a high oxygen consumption,
so insufficient blood supply leads to visual impairment. The incidence of related conditions is …
so insufficient blood supply leads to visual impairment. The incidence of related conditions is …
A murine model of ischemic retinal injury induced by transient bilateral common carotid artery occlusion
Diverse vascular diseases such as diabetic retinopathy, occlusion of retinal veins or arteries
and ocular ischemic syndrome can lead to retinal ischemia. To investigate pathological …
and ocular ischemic syndrome can lead to retinal ischemia. To investigate pathological …
New mouse retinal stroke model reveals direction-selective circuit damage linked to permanent optokinetic response loss
S Joly, A Guzik-Kornacka… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Ischemic insults give rise to severe visual deficits after blood vessel occlusion. In
this study we investigated the effects of retinal stroke on the direction-selective circuit of the …
this study we investigated the effects of retinal stroke on the direction-selective circuit of the …
[HTML][HTML] Proinflammatory cytokines in a mouse model of central retinal artery occlusion
M Kramer, S Dadon, M Hasanreisoglu… - Molecular …, 2009 - ncbi.nlm.nih.gov
Purpose To analyze cytokines in the retina and serum in an experimental model of central
retinal artery occlusion (CRAO) in mice. Methods CRAO was induced by laser activation of …
retinal artery occlusion (CRAO) in mice. Methods CRAO was induced by laser activation of …
Novel acute retinal artery ischemia and reperfusion model in nonhuman primates
Background and Purpose: The retina, as an externally located neural tissue, offers unique
advantages in investigating the effect of therapeutic intervention on the brain. In this study …
advantages in investigating the effect of therapeutic intervention on the brain. In this study …