We report the cases of three elderly patients presenting with insidious mental impairment
whilst receiving both lipophilic and hydrophilic beta-adrenoceptor blocking agents …

A 74-year-old woman with mild dementia became disoriented and developed paranoid
delusions when treated with low-dose propranolol. There was no evidence of cardiovascular …

This report deals with a 54-year-old man with loss of memory. His impaired memory was
found to be due to the atenolol he was on and he made a complete recovery on withdrawing …

SIR,-We read with interest the paper by Dr. DJ Warren and others (27 April, p. 193),
reporting three cases of deterioration of renal function in patients with chronic renal failure …

The use of beta-blockers in elderly patients with hypertension has been questioned owing to
the increased incidence of heart failure in this age group. As our clinical impression at the …

Beta-adrenoceptor blocking drugs (beta-blockers) are a group of drugs with a range of
therapeutic indicationsfl]. They are most commonly used in the treatment of angina and …

SIR,-I should like to support Dr. JR Sibert's comments on camphor poisoning in children (31
March, p. 803). Our experience with this substance at this hospital is in fact less than that in …

The physiological changes which accompany old age are well recognised to cause
alterations in drug disposition (Crooks et al., 1976) but recently it has become apparent that …

During the last four years we have used a new cardioselective β‐adrenergic blocking
substance, ICI 66.082 (atenolol or Tenormin®), alone or in combination with other drugs for …

1 Enalapril 20 mg, propranolol 160 mg, atenolol 50 mg and placebo each were given once a
day for 8 days to 12 normal volunteers, using a Latin‐square design and double‐blind …