There is growing evidence that obesity is a risk factor of cancer incidence and mortality.
Hence, the identification of the mechanistic links between obesity and cancer progression is …

Obesity is an established risk factor for postmenopausal breast cancer. The mechanisms
through which obesity influences the development and progression of breast cancer are not …

Background Obesity in postmenopausal women is associated with increased breast cancer
risk, development of more aggressive tumors and resistance to certain anti-breast cancer …

Perturbations in the adipocytokine profile, especially higher levels of leptin, are a major
cause of breast tumor progression and metastasis; the underlying mechanisms, however …

Obesity is now considered as a risk factor for breast cancer in postmenopausal women.
Adipokine levels are modulated in obesity, and may play a role in carcinogenesis. Moreover …

The escalating epidemic of overweight and obesity is currently recognized as one of the
most significant health and economic concern worldwide. At the present time, over 1.9 billion …

Obesity is a major risk factor for the development and progression of breast cancer. Leptin, a
cytokine mainly produced by adipocytes, plays a crucial role in mammary carcinogenesis …

Purpose: Recent in vitro studies suggested that the autocrine leptin loop might contribute to
breast cancer development by enhancing cell growth and survival. To evaluate whether the …

A number of studies indicate that a growing list of cancers may be influenced by obesity. In
obese individuals these cancers can be more frequent and more aggressive resulting in …

The present case–control study was to investigate the relationships of plasma leptin level
and anthropometric measures of adiposity with the risk of breast cancer. Questionnaire …