Retinoblastoma can present in 1 or both eyes and is the most common intraocular
malignancy in childhood. It is typically initiated by biallelic mutation of the RB1 tumor …

Retinoblastoma is the most common intraocular cancer of childhood (Shields and Shields
2015; JA and CL 1992; Kivela 2009; Ramasubramanian and Shields 2012a). This …

Progressive advances in the understanding of retinoblastoma pathogenesis continue to lead
treatment strategies. Improvements in the diagnosis and management of retinoblastoma are …

Background Retinoblastoma is a highly malignant tumor of the eye that manifests most often
in the first 3 years of life. Methods Published articles were reviewed to evaluate the clinical …

PURPOSE: To provide an overview of the current clinical management of retinoblastoma by
discussing the trends in the categorization, treatment, and recent advances in molecular …

Retinoblastoma represents approximately 4% of all pediatric malignancies and is the most
common primary intraocular cancer in children. 1, 2 Worldwide, it is estimated that there are …

Retinoblastoma is the most common intraocular malignancy in children, with a reported
incidence ranging from 1 in 15,000 to 1 in 18,000 live births. It is second only to uveal …

Purpose To review the progress made in understanding the genetic basis, molecular
pathology, and treatment of retinoblastoma since the previous Jackson lecture on the topic …

Retinoblastoma is the commonest primary ocular malignancy of childhood. There are two
forms—heritable and non heritable. Heritable retinoblastoma is a cancer susceptibility …

Retinoblastoma is the most common neoplasm of the eye in childhood, representing 2.5% to
4% of all pediatric cancers. The average age-adjusted incidence rate of retinoblastoma in …