Using a newly-developed technique, a severe acquired plasma resistance to activated
protein C has been described in women using third-generation (rather than second …

Objective: The object of the study was to determine the effects of oral contraceptives on
blood coagulation, in particular on the protein C pathway. Study Design: Plasma samples …

Resistance to activated protein C (APC-R) is at present considered the most frequent
laboratory abnormality in patients with deep vein thrombosis. An increased risk for venous …

Resistance to activated protein C (APC resistance) is an important and common risk factor
for deep vein thrombosis. The majority of patients with APC resistance carry a mutation on …

Recent studies suggest that low‐dose oral contraceptives may cause acquired resistance to
activated protein C (APC). The aims of this study were to determine whether hormone …

Eighty-one women with a history of thrombosis were classified into three groups: group I (n=
29), women in whom thrombosis developed during oral contraception; group II (n= 33) …

The effect of oral contraceptive therapy was studied in five patients with homozygous
activated protein C resistance. Patients with this congenital abnormality, in contrast to those …

The discovery of plasma resistance towards activated protein C, APC resistance, and its
main genetic background, the presence of a single-point mutation in the gene coding for …

Resistance to activated protein C (APC) is at present considered the most frequent
laboratory abnormality in patients with deep‐vein thrombosis. An increased risk for venous …

Background: Background: We have reported previously that, compared with use of second
generationn oral contraceptives, the use of third generation oral contraceptives iss …