An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway

S Aoki, JB Smith, H Li, X Yan, M Igarashi, P Coulon… - Elife, 2019 - elifesciences.org
Cortico-basal ganglia-thalamocortical loops are largely conceived as parallel circuits that
process limbic, associative, and sensorimotor information separately. Whether and how …

Exponential history integration with diverse temporal scales in retrosplenial cortex supports hyperbolic behavior

BP Danskin, R Hattori, YE Zhang, Z Babic, M Aoi… - Science …, 2023 - science.org
Animals use past experience to guide future choices. The integration of experiences
typically follows a hyperbolic, rather than exponential, decay pattern with a heavy tail for …

Retrosplenial cortical representations of space and future goal locations develop with learning

AMP Miller, W Mau, DM Smith - Current Biology, 2019 - cell.com
Recent findings suggest that long-term spatial and contextual memories depend on the
retrosplenial cortex (RSC)[1–5]. RSC damage impairs navigation in humans and rodents [6 …

Prefrontal cortex modulates firing pattern in the nucleus reuniens of the midline thalamus via distinct corticothalamic pathways

EC Zimmerman, AA Grace - European Journal of Neuroscience, 2018 - Wiley Online Library
The thalamus has long been recognized for its role in relaying sensory information from the
periphery, a function accomplished by its “first‐order” nuclei. However, a second category of …

Shared cortex-cerebellum dynamics in the execution and learning of a motor task

MJ Wagner, TH Kim, J Kadmon, ND Nguyen, S Ganguli… - Cell, 2019 - cell.com
Throughout mammalian neocortex, layer 5 pyramidal (L5) cells project via the pons to a vast
number of cerebellar granule cells (GrCs), forming a fundamental pathway. Yet, it is …

Integration of feedforward and feedback information streams in the modular architecture of mouse visual cortex

A Burkhalter, RD D'Souza, W Ji… - Annual Review of …, 2023 - annualreviews.org
Radial cell columns are a hallmark feature of cortical architecture in many mammalian
species. It has long been held, based on the lack of orientation columns, that such functional …

Spatially patterned excitatory neuron subtypes and projections of the claustrum

SR Erwin, BN Bristow, KE Sullivan, RM Kendrick… - elife, 2021 - elifesciences.org
The claustrum is a functionally and structurally complex brain region, whose very spatial
extent remains debated. Histochemical-based approaches typically treat the claustrum as a …

Genetically distinct parallel pathways in the entopeduncular nucleus for limbic and sensorimotor output of the basal ganglia

ML Wallace, A Saunders, KW Huang, AC Philson… - Neuron, 2017 - cell.com
The basal ganglia (BG) integrate inputs from diverse sensorimotor, limbic, and associative
regions to guide action-selection and goal-directed behaviors. The entopeduncular nucleus …

Granular and dysgranular retrosplenial cortices provide qualitatively different contributions to spatial working memory: Evidence from immediate‐early gene imaging …

HHJ Pothuizen, M Davies, MM Albasser… - European Journal of …, 2009 - Wiley Online Library
The present study revealed striking task‐dependent differences in immediate‐early gene
activity in the two main subregions (granular and dysgranular) of the retrosplenial cortex. In …

Anterior cingulate cortex input to the claustrum is required for top-down action control

MG White, M Panicker, C Mu, AM Carter, BM Roberts… - Cell reports, 2018 - cell.com
Cognitive abilities, such as volitional attention, operate under top-down, executive frontal
cortical control of hierarchically lower structures. The circuit mechanisms underlying this …