Mitochondrial reactive oxygen species production has emerged as an important
pathological mechanism in myocardial ischemia/reperfusion injury. Attempts at targeting …

Despite major progress in interventional and medical treatments, myocardial infarction (MI)
and subsequent development of heart failure (HF) are still associated with high mortality …

Ischaemia/reperfusion (I/R) injury of the heart represents a major health burden mainly
associated with acute coronary syndromes. While timely coronary reperfusion has become …

Coronary arterial disease is the most common cardiovascular disease. Myocardial ischemia-
reperfusion injury caused by the initial interruption of organ blood flow and subsequent …

Reductions in the blood supply produce considerable injury if the duration of ischemia is
prolonged. Paradoxically, restoration of perfusion to ischemic organs can exacerbate tissue …

Reactive oxygen species (ROS) generation has been implicated in many pathologies
including ischemia/reperfusion (I/R) injury. This led to multiple studies on antioxidant …

Thrombolytic therapy and revascularization strategies create a complete recanalization of
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …

Reperfusion therapy must be applied as soon as possible to attenuate the ischemic insult of
acute myocardial infarction (AMI). However reperfusion is responsible for additional …

Reperfusion therapy is the indispensable treatment of acute myocardial infarction (AMI) and
must be applied as soon as possible to attenuate the ischemic insult. However, reperfusion …

Excessive production of free radicals by mitochondria is associated with, and likely
contributes to, the progression of numerous pathological conditions. Nevertheless, the …