Chronic morphine administration differentially modulates viral reservoirs in a simian immunodeficiency virus SIVmac251-infected rhesus macaque model
A Acharya, OA Olwenyi, M Thurman, K Pandey… - Journal of …, 2021 - Am Soc Microbiol
Human immunodeficiency virus (HIV) persists in cellular reservoirs despite effective
combined antiretroviral therapy (cART), and there is viremia flare-up upon therapy …
combined antiretroviral therapy (cART), and there is viremia flare-up upon therapy …
Chronic morphine administration differentially modulates viral reservoirs in SIVmac251 infected rhesus macaque model
A Acharya, OA Olwenyi, M Thurman, K Pandey… - bioRxiv, 2020 - biorxiv.org
HIV persists in cellular reservoirs despite effective anti-retroviral therapy with rebound of
viremia upon therapy interruption. Opioids modulate the immune system and suppress …
viremia upon therapy interruption. Opioids modulate the immune system and suppress …
Role of mu-opioids as cofactors in human immunodeficiency virus type 1 disease progression and neuropathogenesis
A Banerjee, M Strazza, B Wigdahl, V Pirrone… - Journal of …, 2011 - Springer
About one third of acquired immunodeficiency syndrome cases in the USA have been
attributed to the use of injected addictive drugs, frequently involving opioids like heroin and …
attributed to the use of injected addictive drugs, frequently involving opioids like heroin and …
[HTML][HTML] Modeling the effects of morphine-altered virus specific antibody responses on HIV/SIV dynamics
Drugs of abuse, such as opiates, have been widely associated with enhancing HIV
replication, accelerating disease progression and diminishing host-immune responses …
replication, accelerating disease progression and diminishing host-immune responses …
[HTML][HTML] Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs.
N Beliakova-Bethell, R Deiss, S Letendre, M Trunfio… - Viruses, 2023 - escholarship.org
People with HIV are more likely to have opioid use disorder and to be prescribed opioids for
chronic pain than the general population; however, the effects of opioids on the immune …
chronic pain than the general population; however, the effects of opioids on the immune …
[HTML][HTML] Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs
M Trunfio, A Chaillon, N Beliakova-Bethell, R Deiss… - Viruses, 2023 - mdpi.com
People with HIV are more likely to have opioid use disorder and to be prescribed opioids for
chronic pain than the general population; however, the effects of opioids on the immune …
chronic pain than the general population; however, the effects of opioids on the immune …
Morphine potentiates neuropathogenesis of SIV infection in rhesus macaques
SM Bokhari, R Hegde, S Callen, H Yao, I Adany… - Journal of Neuroimmune …, 2011 - Springer
Despite the advent of antiretroviral therapy, complications of HIV-1 infection with concurrent
drug abuse are an emerging problem. Opiates are well known to modulate immune …
drug abuse are an emerging problem. Opiates are well known to modulate immune …
Opioid abuse and SIV infection in non-human primates
Human immunodeficiency virus (HIV) and drug abuse are intertwined epidemics, leading to
compromised adherence to combined antiretroviral therapy (cART) and exacerbation of …
compromised adherence to combined antiretroviral therapy (cART) and exacerbation of …
Morphine promotes simian acquired immunodeficiency syndrome virus replication in monkey peripheral mononuclear cells: induction of CC chemokine receptor 5 …
S Suzuki, AJ Chuang, LF Chuang… - The Journal of …, 2002 - academic.oup.com
Rhesus monkeys {it (Macaca mulatta)} chronically administered opioids were more
susceptible to simian immunodeficiency virus (SIV) strain mac239 (SIVmac239) infection …
susceptible to simian immunodeficiency virus (SIV) strain mac239 (SIVmac239) infection …
[HTML][HTML] Systems biology analyses reveal enhanced chronic morphine distortion of gut-brain interrelationships in simian human immunodeficiency virus infected …
OA Olwenyi, SD Johnson, M Bidokhti… - Frontiers in …, 2022 - frontiersin.org
Background Commonly used opioids, such as morphine have been implicated in
augmented SIV/HIV persistence within the central nervous system (CNS). However, the …
augmented SIV/HIV persistence within the central nervous system (CNS). However, the …