Evolving concepts and translational relevance of enteroendocrine cell biology

DJ Drucker - The Journal of Clinical Endocrinology & …, 2016 - academic.oup.com
Context: Classical enteroenteroendocrine cell (EEC) biology evolved historically from
identification of scattered hormone-producing endocrine cells within the epithelial mucosa of …

Enteroendocrine cell differentiation and function in the intestine

JG Sanchez, JR Enriquez, JM Wells - Current Opinion in …, 2022 - journals.lww.com
Enteroendocrine cell differentiation and function in the int... : Current Opinion in
Endocrinology, Diabetes and Obesity Enteroendocrine cell differentiation and function in …

Enteroendocrine cells in gastrointestinal pathophysiology

E Harrison, S Lal, JT McLaughlin - Current opinion in pharmacology, 2013 - Elsevier
Highlights•EEC dysfunction occurs in a wide array of GI diseases.•EEC dysfunction is
important in GI symptom generation.•EEC dysfunction affects the maintenance of intestinal …

Enteroendocrine cells: neglected players in gastrointestinal disorders?

GW Moran, FC Leslie, SE Levison… - Therapeutic …, 2008 - journals.sagepub.com
Enteroendocrine cells (EEC) form the basis of the largest endocrine system in the body.
They secrete multiple regulatory molecules which control physiological and homeostatic …

Classification and functions of enteroendocrine cells of the lower gastrointestinal tract

AR Gunawardene, BM Corfe… - International journal of …, 2011 - Wiley Online Library
With over thirty different hormones identified as being produced in the gastrointestinal (GI)
tract, the gut has been described as 'the largest endocrine organ in the body'(Ann. Oncol …

Intestinal enteroendocrine cells: present and future druggable targets

R Atanga, V Singh, JG In - International journal of molecular sciences, 2023 - mdpi.com
Enteroendocrine cells are specialized secretory lineage cells in the small and large
intestines that secrete hormones and peptides in response to luminal contents. The various …

[HTML][HTML] The role of microbiota and enteroendocrine cells in maintaining homeostasis in the human digestive tract

D Woźniak, W Cichy, J Przysławski… - Advances in medical …, 2021 - Elsevier
The microbiota is a heterogeneous ecosystem consisting of diverse microorganisms unique
to an individual, playing a crucial role in maintaining human body homeostasis. The …

High-resolution mRNA and secretome atlas of human enteroendocrine cells

J Beumer, J Puschhof, J Bauzá-Martinez… - Cell, 2020 - cell.com
Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate
gastrointestinal activity, systemic metabolism, and food intake. Little is known about the …

Enteroendocrine cells: metabolic relays between microbes and their host

H Plovier, PD Cani - Developmental Biology of Gastrointestinal …, 2017 - karger.com
Gut bacteria exert a variety of metabolic functions unavailable to the host and are
increasingly seen as a virtual organ located inside our gastrointestinal tract. Scattered in our …

The enteroendocrine “letter cells”–time for a new nomenclature?

HF Helander, L Fändriks - Scandinavian journal of …, 2012 - Taylor & Francis
The endocrine cells of the gastrointestinal (GI) tract and the pancreas, referred to as the
enteroendocrine cells, secrete a large variety of peptides and amines that regulate functions …