Cisplatin and other platinum‐based drugs are well‐known valid anticancer drugs. However,
during chemotherapy, the presence of numerous side effects and the onset of frequent …

Background Cancer treatment using gold (I) complexes is becoming popular. In this study, a
gold (I) N-heterocyclic complex designated as complex 3 was synthesized, its cytotoxicity …

The use of gold in medicine has a long history. Recent clinical applications include anti-
inflammatory agents for the treatment of rheumatoid arthritis (chrysotherapy), and is currently …

The discovery of cisplatin in 1965 and its subsequent approval as an anticancer drug in
1978, paved the way for advances in anticancer platinum-based drugs.[1] However, cisplatin …

Transition metal complexes bearing amino linked N-heterocyclic carbenes (NHC) were
prepared and evaluated for their antiproliferative activities in human cancer cells. The …

Abstract Au (NHC) and Au (NHC) 2, ie a monocarbene gold (I) complex and the
corresponding bis (carbene) complex, are two structurally related compounds, endowed …

Herein, we report the synthesis and the multiple anti-tumor properties of new gold and silver
carbene complexes. The chemical modifications, grounded on our previous studies, led us …

Due to their promising effects, gold (III) complexes recently drew increasing attention in the
design of new metal-based anticancer therapeutics. Two gold (III) complexes, square-planar …

Two gold (I) complexes of the (NHC) AuX type bearing a triazole‐based N‐heterocyclic
carbene (NHC) ligand (1‐tert‐butyl‐4‐(4‐methylphenyl)‐3‐phenyl‐1H‐1, 2, 4‐triazol‐4‐ium …

Fourteen silver (I) complexes bearing N‐heterocyclic carbene (NHC) ligands were prepared
and evaluated for anticancer activity. Some of these were found to exhibit potent …