Genetics of plasma lipoprotein (a) concentrations

E Boerwinkle - Current Opinion in Lipidology, 1992 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is a low-density-like lipoprotein with the addition of a Lp (a)-
specific protein, apolipoprotein (a)[apo (a)]. Plasma concentrations of Lp (a) are a risk factor …

[引用][C] Genetic architecture of the atherogenic lipoprotein (a)

G Utermann, C Haibach, M Trommsdorff… - Annals of the New …, 1994 - Wiley Online Library
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait in human plasma that is almost
unaffected by age, diet, or life-style. Thc distribution of Lp (a) plasma concentrations is …

[PDF][PDF] The effect of genetic determinants of low density lipoprotein levels on lipoprotein (a)

PN Hopkins, RR Williams - Clin Invest Med, 1991 - researchgate.net
Abstract Levels of Lipoprotein (a)[Lp (a)] correlate directly with atherosclerosis risk. The Lp
(a) particle is physically and chemically similar to low density lipoprotein (LDL), the main …

Structure, function, and genetics of lipoprotein (a)

K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …

Lipoprotein (a) in health and disease

F Kronenberg, A Steinmetz, GM Kostner… - Critical reviews in …, 1996 - Taylor & Francis
Abstract Lipoprotein (a)[Lp (a)] represents an LDL-like particle to which the Lp (a)-specific
apolipoprotein (a) is linked via a disulfide bridge. It has gained considerable interest as a …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

A Common LPA Null Allele Associates With Lower Lipoprotein(a) Levels and Coronary Artery Disease Risk

T Kyriakou, U Seedorf, A Goel… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Increased levels of lipoprotein (a) are a highly heritable risk factor for coronary
artery disease (CAD). The genetic determinants of lipoprotein (a) levels are mainly because …

Lipoprotein (a): genotype–phenotype relationship and impact on atherogenic risk

B Enkhmaa, E Anuurad, W Zhang, T Tran… - … syndrome and related …, 2011 - liebertpub.com
In 2010, more than 45 years after the initial discovery of lipoprotein (a)[Lp (a)] by Kare Berg,
an European Atherosclerosis Society Consensus Panel recommended screening for …

Genetics and metabolism of lipoprotein (a) and their clinical implications (Part 1).

H Dieplinger, F Kronenberg - Wiener Klinische Wochenschrift, 1999 - europepmc.org
The human plasma lipoprotein Lp (a) has gained considerable clinical interest as a
genetically determined risk factor for atherosclerotic vascular diseases. Numerous (including …

Lipoprotein (a) in homozygous familial hypercholesterolemia

HG Kraft, A Lingenhel, FJ Raal… - … , and vascular biology, 2000 - Am Heart Assoc
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait that in the general population is largely
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …