Characterization of the target cell antigen in I region-mediated lympholysis

HS Teh, M Letarte, RA Phillips, RG Miller - Cellular Immunology, 1978 - Elsevier
Cytotoxic T lymphocytes (CL) can be produced by culturing I region disparate spleen cells
as previously reported. More recently, it was shown that these CL can lyse other target cells …

Lyt phenotypes of primary cytotoxic T cells generated across the A and E region of the H‐2 complex

D Vidovic, A Juretic, ZA Nagy… - European Journal of …, 1981 - Wiley Online Library
Six different cell‐mediated lympholysis (CML) combinations were established, four of which
generated effector cells against the I‐E, and two against the I‐A molecule. The cell surface …

T Lymphocyte-Mediated Cytolysis—A Comprehensive Theory II. Lytic vs. Nonlytic Interactions of T Lymphocytes

WR Clark, G Berke - Mechanisms of Cell-Mediated Cytotoxicity, 1982 - Springer
In the model for CTL-mediated lysis presented in the preceding paper, we postulated that
the binding of CTL to target cells through interaction of an array of MHC-specific T cell …

Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis.

JP Tite, MB Powell, NH Ruddle - Journal of immunology (Baltimore …, 1985 - journals.aai.org
We previously showed that cloned, antigen-specific, Ia-restricted L3T4a+ T cell lines can be
cytolytic for antigen-pulsed B cell lymphoma targets. Such cells can also, under different …

Clonal analysis of cytolytic T lymphocyte-mediated lysis of target cells with inducible antigen expression: correlation between antigen density and requirement for Lyt-2 …

R Shimonkevitz, B Luescher, JC Cerottini… - … (Baltimore, Md.: 1950 …, 1985 - journals.aai.org
The lysis by allospecific cytolytic T lymphocytes (CTL) of the BALB/c lymphoma ST-4.5, a cell
line that can be induced by interferon-gamma (IFN-gamma) to express increased amounts of …

Features of target cell lysis by class I and class II MHC-restricted cytolytic T lymphocytes.

MM Maimone, LA Morrison, VL Braciale… - Journal of immunology …, 1986 - journals.aai.org
The lytic activity of influenza virus-specific murine cytolytic T lymphocyte (CTL) clones that
are restricted by either H-2K/D (class I) or H-2I (class II) major histocompatibility (MHC) locus …

L3T4+ cytotoxic T lymphocytes specific for class I H-2 antigens are activated in primary mixed lymphocyte reactions.

S Macphail, O Stutman - Journal of immunology (Baltimore, Md …, 1987 - journals.aai.org
Abstract Thy-1+, L3T4+, Ly-2-cytotoxic lymphocytes (CTL) are generated in a primary anti-H-
2d mixed lymphocyte reaction, by using responders depleted of Ly-2+ cells. In addition to …

Targeted cytotoxic cells in human peripheral blood lymphocytes.

MA Garrido, P Perez, JA Titus, MJ Valdayo… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have isolated subsets of cells from human PBL and have investigated their abilities to
mediate lysis targeted by bispecific antibodies. Targeted cytotoxic cells were divided into two …

Two functionally distinct subpopulations of human T cells that collaborate in the generation of cytotoxic cells responsible for cell-mediated lympholysis

RL Evans, H Lazarus, AC Penta… - The Journal of …, 1978 - journals.aai.org
A human thymus-dependent differentiation antigen, TH2 was defined by a rabbit anti-human
T cell serum absorbed with autologous B lymphoblasts and leukemic cells bearing T cell …

Suppression of cell‐mediated lymphocytotoxicity against minor histocompatibility antigens mediated by Lyt‐1+Lyt−2+ T cells of stimulator‐strain origin

HG Rammensee, ZA Nagy… - European Journal of …, 1982 - Wiley Online Library
Cultured, unprimed spleen cells suppress the generation of cytolytic T lymphocytes when
added to mixed lymphocyte culture of cells disparate at minor histocompatibility (H) loci …