[HTML][HTML] Harmonisation of osmolal gap–can we use a common formula?

KW Choy, N Wijeratne, ZX Lu… - The Clinical Biochemist …, 2016 - ncbi.nlm.nih.gov
Osmolal gap is the difference between the measured osmolality and a calculated osmolality
based on the major commonly measured osmotically active particles. The perceived gap …

Choice of the best equation for plasma osmolality calculation: comparison of fourteen formulae

JL Martín-Calderón, F Bustos, LR Tuesta-Reina… - Clinical …, 2015 - Elsevier
Background Many different equations have been previously described to estimate plasma
osmolality. The aim of this study is to compare 14 of these equations, in order to determine …

Derivation and validation of a new formula for plasma osmolality estimation

JL Martín-Calderón, LR Tuesta-Reina - Clinical Biochemistry, 2022 - Elsevier
Background Plasma osmolality is a physic and chemical property of interest in emergency
medicine. This magnitude can be measured at the laboratory, but it is usually estimated with …

The irrationality of the present use of the osmole gap: applicable physical chemistry principles and recommendations to improve the validity of current practices

Y Koga, RA Purssell, LD Lynd - Toxicological reviews, 2004 - Springer
The present clinical use of serum osmometry is erroneous in two respects. The first, and the
most important, is the incorrect assumption that serum behaves as a dilute 'ideal'solution …

The osmolal gap: what has changed?

JDE Whittington, SL La'ulu, JJH Hunsaker… - Clinical …, 2010 - academic.oup.com
The osmolal gap (OG) 1 is calculated in the emergency department (ED) when ingestion of
ethylene glycol, methanol, isopropyl alcohol, acetone, or other osmotically active substances …

Critical evaluation of equations for serum osmolality: Proposals for effective clinical utility

EO Ebonwu, SE Nagel, L Repsold, TS Pillay - Clinica Chimica Acta, 2020 - Elsevier
Background Many studies have assessed the predictive accuracy of serum osmolality
equations. Different approaches for selecting a usable equation were compared using thirty …

Serum osmolal gap

M Emmett, BF Palmer - Uptodate Version, 2020 - uptodate.com
Osmolality is a measurement of the number of moles of dissolved particles per kg of solvent
(for clinical purposes, water is the solvent). Osmolarity is a measure of the number of …

Osmolality revisited—deriving and validating the best formula for calculated osmolality

A Khajuria, J Krahn - Clinical biochemistry, 2005 - Elsevier
OBJECTIVE:: To derive a formula that can be used (i) to calculate osmolality in normal
patients as well as those that are hyperglycemic and intoxicated, and (ii) to predict the …

Comparison of methods for calculating serum osmolality: multivariate linear regression analysis

M Rasouli, KR Kalantari - Clinical Chemistry and Laboratory …, 2005 - degruyter.com
Background: There are several methods for calculating serum osmolality, and their
accordance with measured osmolality is the subject of controversy. Methods: The …

Evaluation of 36 formulas for calculating plasma osmolality

AS Fazekas, GC Funk, DS Klobassa, H Rüther… - Intensive care …, 2013 - Springer
Purpose Measuring or calculating plasma osmolality is of interest in critical care medicine.
Moreover, the osmolal gap (ie the difference between the measured and calculated …