Peptidyl-prolyl isomerase Cyclophilin71 promotes SERRATE phase separation and miRNA processing in Arabidopsis

G Zhao, J Niu, Z Hai, T Li, D Xie… - Proceedings of the …, 2023 - National Acad Sciences
MicroRNAs (miRNAs) play an important role in gene regulation. In Arabidopsis, mature
miRNAs are processed from primary miRNA transcripts by the Dicing complex that contains …

Transcription and processing of primary microRNAs are coupled by Elongator complex in Arabidopsis

X Fang, Y Cui, Y Li, Y Qi - Nature Plants, 2015 - nature.com
MicroRNAs (miRNAs) are a class of small non-coding RNAs that play important regulatory
roles in gene expression in plants and animals. The biogenesis of miRNAs involves the …

Phase separation of SERRATE drives dicing body assembly and promotes miRNA processing in Arabidopsis

D Xie, M Chen, J Niu, L Wang, Y Li, X Fang, P Li… - Nature Cell …, 2021 - nature.com
MicroRNA (miRNA) production entails the step-wise processing of primary miRNAs (pri-
miRNAs) into precursor miRNAs (pre-miRNAs) and miRNA/* duplexes by Dicing complexes …

The helicase and RNaseIIIa domains of Arabidopsis Dicer-Like1 modulate catalytic parameters during microRNA biogenesis

C Liu, MJ Axtell, NV Fedoroff - Plant physiology, 2012 - academic.oup.com
Abstract Dicer-Like1 (DCL1), an RNaseIII endonuclease, and Hyponastic Leaves1 (HYL1), a
double-stranded RNA-binding protein, are core components of the plant microRNA (miRNA) …

Complementation of Hyponastic Leaves1 by Double-Strand RNA-Binding Domains of Dicer-Like1 in Nuclear Dicing Bodies

Q Liu, Q Yan, Y Liu, F Hong, Z Sun, L Shi… - Plant …, 2013 - academic.oup.com
MicroRNAs (miRNA s) are a class of small regulatory RNAs that are found in almost all of the
eukaryotes. Arabidopsis (Arabidopsis thaliana) miRNA s are processed from primary miRNA …

Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis microRNA precursor processing

Y Iwata, M Takahashi, NV Fedoroff… - Nucleic acids …, 2013 - academic.oup.com
Efficient and precise microRNA (miRNA) biogenesis in Arabidopsis is mediated by the
RNaseIII-family enzyme DICER-LIKE 1 (DCL1), double-stranded RNA-binding protein …

The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1

Z Dong, MH Han, N Fedoroff - Proceedings of the National …, 2008 - National Acad Sciences
The results of genetic studies in Arabidopsis indicate that three proteins, the RNase III
DICER-Like1 (DCL1), the dsRNA-binding protein HYPONASTIC LEAVES1 (HYL1), and the …

PRP4KA phosphorylates SERRATE and promotes its degradation to coordinate miRNA production

V Mishra, B Maurya - Journal of Plant Biochemistry and Biotechnology, 2023 - Springer
The precise regulation of miRNA is crucial for plant growth and fitness, which requires the
presence of a core microprocessor composed of DICER-LIKE 1 (DCL1), HYPONASTIC …

Serrate‐Associated Protein 1, a splicing‐related protein, promotes miRNA biogenesis in Arabidopsis

M Li, H Yu, K Liu, W Yang, B Zhou, L Gan, S Li… - New …, 2021 - Wiley Online Library
MicroRNAs (miRNAs) are essential regulators of gene expression in metazoans and plants.
In plants, most miRNAs are generated from primary miRNA transcripts (pri‐miRNAs), which …

[HTML][HTML] Negative feedback regulation of Dicer-Like1 in Arabidopsis by microRNA-guided mRNA degradation

Z Xie, KD Kasschau, JC Carrington - Current Biology, 2003 - cell.com
Formation of microRNA (miRNA) requires an RNaseIII domain-containing protein, termed
DICER-1 in animals and DICER-LIKE1 (DCL1) in plants, to catalyze processing of an RNA …