The functionalization of degradable polymeric scaffolds with therapeutic molecules such as
vascular endothelial growth factor (VEGF) is a key strategy to gain better regenerative ability …

Regenerative engineering approaches utilizing biomimetic synthetic scaffolds provide
alternative strategies to repair and restore damaged bone. The efficacy of the scaffolds for …

Adequate vascularization of tissue-engineered constructs remains a major challenge in
bone grafting. In view of this, we loaded ß-tricalcium-phosphate (ß-TCP) and porous poly (L …

Vascular endothelial growth factor (VEGF) is one of the most crucial growth factors and an
assistant for the adjustment of bone regeneration. In this study, a 3D scaffold is fabricated …

A major limitation with current tissue‐engineering approaches is creating functionally
vascularized constructs that can successfully integrate with the host; this often leads to …

Bone tissue engineering is sought to apply strategies for bone defects healing without
limitations and short-comings of using either bone autografts or allografts and xenografts …

Vascularization is the main obstacle for the bone tissue engineering strategies since the
defect size is generally large. Incorporation of angiogenic factors is one of the strategies …

Natural bone is a highly vascularized tissue that relies on the vasculature for blood and
nutrients supply to maintain skeletal integrity. Inadequacy of neovascularization may …

Purpose Poly (lactic-co-glycolic acid)(PLGA) is excellent as a scaffolding matrix due to
feasibility of processing and tunable biodegradability, yet the virgin scaffolds lack …

The utilization of electrospun biodegradable scaffolds by fine‐tuning their biofunctionalities
through a simple mixing method was demonstrated in this study. Poly (l‐lactide)(PLLA) …