The genomics of schizophrenia: update and implications
P Giusti-Rodríguez, PF Sullivan - The Journal of clinical …, 2013 - Am Soc Clin Investig
Schizophrenia is strongly familial yet rarely (if ever) exhibits classical Mendelian inheritance
patterns. The advent of large-scale genotyping and sequencing projects has yielded large …
patterns. The advent of large-scale genotyping and sequencing projects has yielded large …
New discoveries in schizophrenia genetics reveal neurobiological pathways: a review of recent findings
Schizophrenia research has undergone a recent transformation. By leveraging large sample
sizes, genome-wide association studies of common genetic variants have approximately …
sizes, genome-wide association studies of common genetic variants have approximately …
The genetic architecture of schizophrenia: new mutations and emerging paradigms
L Rodriguez-Murillo, JA Gogos… - Annual review of …, 2012 - annualreviews.org
Although a genetic component of schizophrenia has been acknowledged for a long time, the
underlying architecture of the genetic risk remains a contentious issue. Early linkage and …
underlying architecture of the genetic risk remains a contentious issue. Early linkage and …
Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era
G Costain, AS Bassett - The application of clinical genetics, 2012 - Taylor & Francis
Schizophrenia is a complex neuropsychiatric disease with documented clinical and genetic
heterogeneity, and evidence for neurodevelopmental origins. Driven by new genetic …
heterogeneity, and evidence for neurodevelopmental origins. Driven by new genetic …
Schizophrenia genetics: emerging themes for a complex disorder
DH Kavanagh, KE Tansey, MC O'Donovan… - Molecular …, 2015 - nature.com
After two decades of frustration, genetic studies of schizophrenia have entered an era of
spectacular success. Advances in genotyping technologies and high throughput …
spectacular success. Advances in genotyping technologies and high throughput …
Genetics of schizophrenia
I Escudero, M Johnstone - Current psychiatry reports, 2014 - Springer
The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet
recent studies, especially in the past year, have confirmed genetics as the major cause of …
recent studies, especially in the past year, have confirmed genetics as the major cause of …
Schizophrenia genomics: genetic complexity and functional insights
Determining the causes of schizophrenia has been a notoriously intractable problem,
resistant to a multitude of investigative approaches over centuries. In recent decades …
resistant to a multitude of investigative approaches over centuries. In recent decades …
Genetic architecture of schizophrenia: a review of major advancements
SE Legge, ML Santoro, S Periyasamy… - Psychological …, 2021 - cambridge.org
Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …
technological advancements have led to a substantial increase in knowledge of the genetic …
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
S Ripke, C O'dushlaine, K Chambert, JL Moran… - Nature …, 2013 - nature.com
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …
Genetics of schizophrenia: ready to translate?
Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …
understanding of the genetic architecture of schizophrenia. In this review, we consider how …