Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …

The human lung is continually exposed to airborne conidia of the fungus Aspergillus
fumigatus (AF) and related species. The innate immune system efficiently eliminates inhaled …

Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …

Invasive aspergillosis (IA) remains a devastating disease in immune compromised patients
despite significant advances in our understanding of fungal virulence and host defense …

Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …

The innate host defense system (IHDS) against Aspergillus fumigatus includes dedicated
phagocytic cells (peripheral blood monocytes, monocyte derived macrophages, pulmonary …

Mycotic infections and their effect on the human condition have been widely overlooked and
poorly surveilled by many health organizations even though mortality rates have increased …

Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …

The interplay between Aspergillus fumigatus and the host immune response in lung
infection has been subject of studies over the last years due to its importance in …

Fungi are the most important eukaryotic infective agents in Europe which largely overpass
parasite infections. Total number of people dying of fungal infection is increasing and this …