[HTML][HTML] Matrix degradation in osteoarthritis primes the superficial region of cartilage for mechanical damage

ME Cooke, BM Lawless, SW Jones, LM Grover - Acta Biomaterialia, 2018 - Elsevier
Osteoarthritis (OA) is a degenerative disease that affects 25% of the world's population over
fifty years of age. It is a chronic disease of the synovial joints, primarily the hip and knee. The …

The contribution of bone and cartilage to the near-infrared spectrum of osteochondral tissue

CM McGoverin, K Lewis, X Yang… - Applied …, 2014 - journals.sagepub.com
Near-infrared (NIR) spectroscopy has been used to assess hyaline cartilage quality in
human and animal osteochondral tissues. However, due to the lack of NIR signal from bone …

Association between quantitative MRI and ICRS arthroscopic grading of articular cartilage

V Casula, J Hirvasniemi, P Lehenkari, R Ojala… - Knee Surgery, Sports …, 2016 - Springer
Purpose To investigate the association of quantitative magnetic resonance imaging (qMRI)
parameters with arthroscopic grading of cartilage degeneration. Arthroscopy of the knee is …

[HTML][HTML] High-resolution optical coherence tomographic imaging of osteoarthritic cartilage during open knee surgery

X Li, S Martin, C Pitris, R Ghanta, DL Stamper… - Arthritis Res Ther, 2005 - Springer
This study demonstrates the first real-time imaging in vivo of human cartilage in normal and
osteoarthritic knee joints at a resolution of micrometers, using optical coherence tomography …

[HTML][HTML] Viscoelasticity of the articular cartilage surface in early osteoarthritis

J Desrochers, MW Amrein, JR Matyas - Osteoarthritis and cartilage, 2012 - Elsevier
OBJECTIVE: Structural and biochemical changes in articular cartilage occur throughout the
pathogenesis of osteoarthritis (OA). Early changes include proteoglycan loss and collagen …

Diagnosis of osteoarthritis by cartilage surface smoothness quantified automatically from knee MRI

S Tummala, AC Bay-Jensen, MA Karsdal… - Cartilage, 2011 - journals.sagepub.com
Objective: We investigated whether surface smoothness of articular cartilage in the medial
tibiofemoral compartment quantified from magnetic resonance imaging (MRI) could be …

Physical indicators of cartilage health: the relevance of compliance, thickness, swelling and fibrillar texture

ND Broom, R Flachsmann - Journal of Anatomy, 2003 - Wiley Online Library
This study uses a bovine patella model to compare the relative merits of on‐bone
compliance and thickness measurements, free‐swelling behaviour, and structural imaging …

[HTML][HTML] In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging

S Cotofana, F Eckstein, W Wirth, RB Souza, X Li… - European …, 2011 - Springer
Objective To explore and to compare the magnitude and spatial pattern of in vivo
femorotibial cartilage deformation in healthy and in osteoarthritic (OA) knees. Methods One …

A Framework for the in Vivo Pathomechanics of Osteoarthritis at the Knee

TP Andriacchi, A Mündermann, RL Smith… - Annals of biomedical …, 2004 - Springer
The in vivo pathomechanics of osteoarthritis (OA) at the knee is described in a framework
that is based on an analysis of studies describing assays of biomarkers, cartilage …

Grading of osteoarthritic cartilage: Correlations between histology and biomechanics.

CT Hung, GA Ateshian - Journal of Orthopaedic Research, 2016 - search.ebscohost.com
Grading of osteoarthritic cartilage: Correlations between histology and biomechanics Page 1
COMMENTARY Grading of Osteoarthritic Cartilage: Correlations Between Histology and …