[PDF][PDF] In silico investigation of potential therapeutic medication for the inhibition of dengue virus (DENV NS2B/NS3 and NS1) by modification of polycyclic quaternary …

S Akash, F Arefin, FI Aovi - globe, 2020 - biointerfaceresearch.com
Dengue fever, spread by mosquitoes, has emerged as one of the world's most significant
infectious diseases. To replicate and generate more copies of itself inside the host cell, the …

Targeting a conserved pocket (n-octyl-β-D–glucoside) on the dengue virus envelope protein by small bioactive molecule inhibitors

P Naresh, A Selvaraj, P Shyam Sundar… - Journal of …, 2022 - Taylor & Francis
Dengue virus enters the cell by receptor-mediated endocytosis followed by a viral envelope
(DENVE) protein-mediated membrane fusion. A small detergent molecule n-octyl-β-D …

[HTML][HTML] Docking and QM/MM Studies of NS2B-NS3pro Inhibitors: A molecular target against the dengue virus

IP Godói, WG Lima, M Comar, RJ Alves… - Journal of the Brazilian …, 2017 - SciELO Brasil
Dengue virus (DENV) has been characterized as having great clinical importance in the
world, as there is no specific treatment against this virus. The NS2B-NS3pro complex is …

[PDF][PDF] Active Sites and Potential Inhibitors Prediction for Nonstructural 4A Protein of Dengue Virus

A Ali, T Rehman, N uddin Ahmad, R Ali… - International Journal of …, 2014 - researchgate.net
Dengue virus is transmitted to human by mosquitoes. The virus has the potential to expand
globally and is responsible for a wide range of clinical manifestations which result in an …

A transcriptomics-based bioinformatics approach for identification and in vitro screening of FDA-approved drugs for repurposing against dengue virus-2

M Punekar, B Kasabe, P Patil, MB Kakade, D Parashar… - Viruses, 2022 - mdpi.com
The rising incidence of dengue virus (DENV) infections in the tropical and sub-tropical
regions of the world emphasizes the need to identify effective therapeutic drugs against the …

[PDF][PDF] In-silico Design of Oxadiazole Hybrids as Potential Inhibitors of Dengue Virus NS2B-NS3 Protease

S Adawara, G Adamu, P Mamza, I Abdulkadir - Adv. J. Chem. Sec. A., 2022 - sid.ir
Dengue virus is an important class of virus of the Flavivirus family that is accountable for the
major cause of dengue fever, which could progress to dengue shock syndrome (DSS) which …

[PDF][PDF] In silico molecular modelling and docking studies on therapeutic target non structural protein 3 (NS3) of dengue virus 1

S Komala, S Ravi, P Usnantaj, B Shanmugam… - Int J Pharmaceut Sci … - researchgate.net
Dengue virus (DENV) is a family member of flaviviruses, transfer their pathogenecity to
humans by the vector mosquitoes and it is showing similar positive sense genomic RNA as …

Development of antiviral inhibitor against dengue 2 targeting Ns3 protein: In vitro and in silico significant studies

P Padmapriya, SG Fathima, G Ramanathan, V Yuvaraj… - Acta tropica, 2018 - Elsevier
Dengue fever is a severe, widespread disease with more than 2 million diagnosed infections
per year. The Dengue virus protease represents a cardinal target for prudent drug design …

Antiviral activity of an indole-type compound derived from natural products, identified by virtual screening by interaction on dengue virus NS5 protein

LL García-Ariza, N González-Rivillas, CJ Díaz-Aguirre… - Viruses, 2023 - mdpi.com
Dengue is an acute febrile illness caused by the Dengue virus (DENV), with a high number
of cases worldwide. There is no available treatment that directly affects the virus or the viral …

A multi-target approach for discovery of antiviral compounds against dengue virus from green tea

P Mahajan, S Tomar, A Kumar, N Yadav, A Arya… - … Modeling Analysis in …, 2020 - Springer
Dengue virus (DENV) infection is one of the largest threats worldwide, and there is no any
specific drug available in the market to combat its serious causes. In the present study, we …