Targeting the tumor vasculature is an attractive strategy for cancer treatment. However, the
tumor vasculature is heterogeneous, and the mechanisms involved in the …

Background Hypoxia induced by antiangiogenic agents is linked to the generation of cancer
stem cells (CSCs) and treatment failure through unknown mechanisms. The generation of …

Agents that target angiogenesis have shown limited efficacy for human triple-negative breast
cancer (TNBC) in clinical trials. Along with endothelium-dependent vessels, there is also …

In 1999, Maniotis reported that blood vessels of highly aggressive uveal melanomas are
formed by tumor cells instead of endothelial cells. He termed this novel concept in tumor …

Tumor angiogenesis is an essential process for growth and metastasis of cancer cells as it
supplies tumors with oxygen and nutrients. During tumor angiogenesis, many pro …

Vasculogenic mimicry (VM) is the formation of a “vessel-like” structure without endothelial
cells. VM exists in vascular-dependent solid tumors and is a special blood supply source …

In the present study, we examined hemodynamics in vasculogenic mimicry (VM) and
angiogenesis of inflammatory breast cancer (IBC) xenografts (WIBC-9), having previously …

The term vasculogenic mimicry (VM) refers to the capacity of certain cancer cells to form fluid-
conducting structures within a tumor in an endothelial cell (EC)-free manner. Ever since its …

Canine mammary gland tumor (CMT) is one of the most important tumors in intact female
dogs, and due its similarity to human breast cancer (BC), it is considered a model in …

Background Vasculogenic mimicry (VM) has been reported in various malignant tumours
and is known to play an important role in cancer progression and metastasis. However, the …