Cognitive impairment is a core clinical feature of traumatic brain injury (TBI). After TBI,
cognition is a key determinant of post-injury productivity, outcome, and quality of life. As a …

Batteries of functional and cognitive measures have been proposed as alternatives to the
Extended Glasgow Outcome Scale (GOSE) as the primary outcome for traumatic brain injury …

Under the auspices of the American Brain Injury Consortium and the Joint Section of
Neurotrauma and Critical Care of the American Association of Neurological Surgeons, the …

The purpose of this study was to conduct an overview of systematic reviews (SRs) to
appraise the published evidence related to pharmacological interventions after traumatic …

Despite the large number of promising neuroprotective agents identified in experimental
traumatic brain injury (TBI) studies, none has yet shown meaningful improvements in long …

Despite indications that TBI may be a precursor of cognitive decline and subsequent
development of Alzheimer's disease, little is known about the time course of this relationship …

Abstract A CONFERENCE WAS held in Houston, Texas, on October 8–9, 1991, to develop
recommendations for outcome measures for clinical trials in traumatic brain injury …

Traumatic brain injury (TBI) is a devastating disease, predominantely affecting young
people. Although the prognosis for TBI victims has improved in recent years, many survivors …

Abstract The Traumatic Brain Injury Endpoints Development (TED) Initiative is a 5-year,
Department of Defense–funded project that is working toward the ultimate goal of …

Traumatic brain injury (TBI) results in disparate outcomes ranging from persistent disorders
of consciousness to symptom resolution. Despite the breadth and complexity of TBI …