In active rheumatoid arthritis, large numbers of granulocytes and macrophages are found in
the inflamed joints. These leucocytes can promote inflammation and tissue injury by …

To investigate if granulocyte and monocyte apheresis mitigates the symptoms of rheumatoid
arthritis (RA), and influences production of panmyelocytes (CD15+ CD16–cells) at the bone …

Rheumatoid arthritis (RA) is an inflammatory condition, the etiology of which is not well
understood. Recent reports indicate a major role of granulocytes in the pathogenesis of RA; …

Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

Objective. To assess the efficacy and safety of adsorptive granulocyte and monocyte
apheresis (GCAP) in patients with refractory rheumatoid arthritis (RA). Methods. Patients …

Pro‐inflammatory cytokines are involved in the pathogenesis of inflammatory skin diseases
attributable to activated neutrophils and macrophages. Myeloid‐derived suppressor cells …

Objective: Dramatic improvements in clinical symptoms of rheumatoid arthritis and ulcerative
colitis were observed after patients received granulocyte and monocyte adsorptive …

The G‐1 column is an extracorporeal type granulocytapheresis device packed with 220 g
cellulose acetate beads to which granulocytes and monocytes specifically adhere. A total of …

Objective Apoptotic cells participate in maintenance of homeostasis of the adaptive immune
system. Granulocyte/monocyte adsorptive apheresis (GMA) performed with an Adacolumn …

To elucidate the molecular mechanisms involved in the therapeutic effects of
granulocyte/monocyte adsorption apheresis, changes were investigated in the cytokine …