S. aureus induced septic arthritis remains a serious medical concern due to its rapidly
progressive disease profile. The multidrug resistant nature of S. aureus demands the …

Objective. To investigate the effect of the synovial fluid from knee joints of rheumatoid
arthritis (RA) patients with different severities of joint destruction on osteoclastogenesis and …

Purpose Two of the most common joint diseases are rheumatoid arthritis (RA) and
osteoarthritis (OA). Cartilage degradation and erosions are important pathogenetic …

Background: Monocytes/macrophages have an important and versatile role in joint
inflammation and destruction in rheumatoid arthritis (RA). Objective: To determine the …

Objective To determine whether myeloid cells (such as granulocytes) present in the synovial
fluid (SF) of arthritic joints have an impact on adaptive immunity. Specifically, we …

Objective To determine if T cells stimulate synovial fibroblasts to produce inflammatory
cytokines through cellular adhesion in synovitis of rheumatoid arthritis (RA). Methods …

Introduction Polymorphonuclear leukocytes (PMN) are main effector cells in the acute
immune response. While the specific role of PMN in systemic lupus erythematosus (SLE) …

Tumour necrosis factor (TNF)-α, interleukin-1β, interleukin-8 and leukotriene B4 have an
important role on neutrophil recruitment during immune-inflammation. Here we evaluated …

The present experiments were designed to investigate in vitro interactions between
polymorphonuclear leukocytes (PMN) and rabbit joint collagenous tissues containing …

Objective Even though there are clinical trials assessing granulocyte–macrophage colony‐
stimulating factor (GM‐CSF) blockade in rheumatoid arthritis (RA), questions remain as to …