Cytogenetically cryptic insertion of PML segment into RARA on chromosome 17q resulting PML-RARA fusion in acute promyelocytic leukemia
TF Burns, EY Loo, EM Bengtson, L Bao - Annals of Hematology, 2019 - Springer
Dear Editor, Acute promyelocytic leukemia (APL) represents 5–8% of acute myeloid
leukemias (AML), and is characterized by the classic t (15; 17)(q24. 1; q21. 2) translocation …
leukemias (AML), and is characterized by the classic t (15; 17)(q24. 1; q21. 2) translocation …
Successful allogeneic bone marrow transplantation in a case of variant acute promyelocytic leukemia with ZBTB16-RARA
S Morimoto, T Kondo, T Taya, H Matsuo… - Annals of …, 2022 - Springer
Dear Editor, Acute promyelocytic leukemia (APL) is a distinct form of acute myeloid leukemia
characterized by reciprocal chromosome translocation t (15; 17)(q24; q21), resulting in the …
characterized by reciprocal chromosome translocation t (15; 17)(q24; q21), resulting in the …
Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in …
JJ Yang, TS Park, MJ Kim, EH Cho, SH Oh… - Annals of …, 2012 - Springer
Dear Editor, In the recent published article “FISH-negative cryptic PMLRARA
rearrangements detected by long-distance polymerase chain reaction and sequencing …
rearrangements detected by long-distance polymerase chain reaction and sequencing …
Co-existence of a novel translocation t(11;22)(q23;q12.1) with PML-RARA in acute promyelocytic leukemia: a case report
WY Shin, JA Kim, SY Yoon, HI Bang, JH Won… - Annals of …, 2022 - Springer
Acute promyelocytic leukemia (APL) is a distinct subset of acute myeloid leukemia (AML),
characterized by a PML-RARA fusion, which acquisition of secondary genetic abnormalities …
characterized by a PML-RARA fusion, which acquisition of secondary genetic abnormalities …
An atypical PML-RARA rearrangement resulting from submicroscopic insertion of the RARA gene at the PML locus with novel breakpoints within PML Exon 7b and …
Y Cao, L Yao, Y Liu, Q Gu, W Dong, Z Wang… - Acta …, 2019 - karger.com
The diagnostic hallmark of acute promyelocytic leukemia (APL) is the reciprocal
translocation t (15; 17), resulting in the characteristic PML-RARA fusion; however, patients …
translocation t (15; 17), resulting in the characteristic PML-RARA fusion; however, patients …
Cytogenetically cryptic and FISH-negative PML/RARA rearrangement in acute promyelocytic leukemia detected only by PCR: an exceedingly rare phenomenon
EM Blanco, CV Curry, XY Lu, SF Sarabia… - Cancer …, 2014 - cancergeneticsjournal.org
Acute promyelocytic leukemia (APL), which comprises 5e7% of acute myeloid leukemias, is
classically characterized by a reciprocal translocation t (15; 17)(q22; q21), resulting in the …
classically characterized by a reciprocal translocation t (15; 17)(q22; q21), resulting in the …
Characterization of a cryptic PML-RARA fusion by mate-pair sequencing in a case of acute promyelocytic leukemia with a normal karyotype and negative RARA …
MJ Schultz, PR Blackburn, CH Cogbill… - Leukemia & …, 2020 - Taylor & Francis
Acute promyelocytic leukemia (APL) is a time-critical hematologic neoplasm that is
amenable to targeted therapy [1]. While the diagnosis of APL can be suspected based on …
amenable to targeted therapy [1]. While the diagnosis of APL can be suspected based on …
Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia
MJ Kim, JJ Yang, C Meyer… - The Korean journal …, 2012 - synapse.koreamed.org
TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean
Journal of Hematology titled,“ZBTB16-RARA variant of acute promyelocytic leukemia with …
Journal of Hematology titled,“ZBTB16-RARA variant of acute promyelocytic leukemia with …
A unique PML-RARα rearrangement involving chromosomes 11, 15, and 17 in a patient with acute promyelocytic leukemia
Acute promyelocytic leukemia (APL) is a rare subtype of acute myeloid leukemia,
characterized by an accumulation of abnormal promyelocytes in the bone marrow, a severe …
characterized by an accumulation of abnormal promyelocytes in the bone marrow, a severe …
[引用][C] Acute promyelocytic leukemia with i(17)(q10) on G‐banding and PML/RARA rearrangement by RT‐PCR without evidence of PML/RARA rearrangement on …
J Huh, H Moon, H Chi, W Chung - International Journal of …, 2009 - Wiley Online Library
The cytogenetic hallmark of acute promyelocytic leukemia (APL) is t (15; 17)(q22; q21)
involving the PML gene on chromosome 15q22 and the RARA gene on chromosome …
involving the PML gene on chromosome 15q22 and the RARA gene on chromosome …