Isotypic and IgG subclass restriction of the humoral immune responses to human T-lymphotropic virus type-I

RB Lal, C Buckner, RF Khabbaz, JE Kaplan… - Clinical immunology and …, 1993 - Elsevier
We have investigated the isotypic and IgG subclass profile of the antibody response to HTLV-
I structural proteins (gag and env) in patients with HTLV-I-associated myelopathy (HAM; n …

Characterization of human T-lymphotropic virus type I-and II-infected T-cell lines: antigenic, phenorypic, and genotypic analysis

CS Dezzutti, DL Rudolph, CR Roberts, RB Lal - Virus research, 1993 - Elsevier
Eighteen long-term T-cell lines were established from peripheral blood mononuclear cells of
individuals infected with human T-lymphotropic virus type I (HTLV-I) or II (HTLV-II). These …

Differential antibody responsiveness to p19 Gag results in serological discrimination between human T lymphotropic virus type I and type II

RB Lal, SK Brodine, JE Coligan… - Journal of medical …, 1991 - Wiley Online Library
A new algorithm based upon the differential antibody responses to two gag gene products
(p19 and p24) of human T lymphotropic virus (HTLV) has been suggested for serologic …

Characterization of antibody reactivity to human T-cell lymphotropic virus types I and II using immunoblot and radioimmunoprecipitation assays

TM Hartley, RF Khabbaz, RO Cannon… - Journal of clinical …, 1990 - Am Soc Microbiol
We have characterized the immunoreactivity to human T-cell lymphotropic virus type I (HTLV-
I) among 26,983 persons of various seroprevalence groups by using enzyme immunoassay …

Serologic differentiation of human T lymphotropic virus type I from type II infection by synthetic peptide immunoassays

CR Roberts, R Mitra, K Hyams… - Journal of medical …, 1992 - Wiley Online Library
Synthetic peptide‐based serologic assays (Select‐HTLV and SynthEIA) that distinguish the
closely related human T‐cell lymphotropic virus types I (HTLV‐I) and II (HTLV‐II) were tested …

Viral-specific humoral immune responses following transfusion-related transmission of human T cell lymphotropic virus type-I infection

A Manns, RJ Wilks, B HANCHARD… - Viral …, 1994 - liebertpub.com
The immunoglobulin (Ig) isotypes of antibodies to specific proteins of the human T cell
lymphotropic virus type I (HTLV-I) were determined by Western blot analysis of serial …

Cloning and analysis of a recombinant antigen containing an epitope specific for human T-cell lymphotropic virus type II

KG Hadlock, JJ Lipka, TP Chow, SK Foung, GR Reyes - 1992 - ashpublications.org
An immunodominant HTLV-I-specific epitope in the HTLV-I envelope glycoprotein (GP) 46
has been described. To determine if the analogous region of HTLV-II contains a similarly …

Identification of immunodominant epitopes in envelope glycoprotein of human T lymphotropic virus type II

RB Lal, DL Rudolph, JE Kaplan, B Hjelle, PH Levine… - Virology, 1992 - Elsevier
A series of synthetic peptides derived from the envelope glycoprotein of human T
lymphotropic virus type II (HTLV-II) was used in an enzyme immunoassay to determine the …

Serologic distinction between human T‐lymphotropic virus (HTLV) type I and HTLV type II

B Hjelle, S Cyrus, S Swenson, R Mills - Transfusion, 1991 - Wiley Online Library
In November 1988, the Food and Drug Administration approved reagents for serologic
screening for human T‐lymphotropic virus type I (HTLV‐I) infection in blood donors and …

Detection and differentiation of antibodies to human T-cell lymphotropic virus types I and II by the immunofluorescence method

D Gallo, LM Penning, CV Hanson - Journal of Clinical …, 1991 - Am Soc Microbiol
We compared the sensitivities of the prototype human T-cell lymphotropic virus type I (HTLV-
I)-and HTLV-II-transformed cell lines, MT2 and Mo-T, with that of an HTLV-II-infected cell …