Cisplatin is an effective antineoplastic agent widely used in the treatment of solid tumors,
however, it induces nephrotoxicity. Cisplatin-induced nephrotoxicity is associated with …

Acute kidney injury (AKI) is a clinical syndrome characterized by morbidity, mortality, and
cost. Cis-diamminedichloroplatinum (cisplatin) is a chemotherapeutic agent used to treat …

Cisplatin (CP) is a chemotherapeutic drug used to treat solid tumors. However, studies have
revealed its nephrotoxic effect. Oxidative stress, endoplasmic reticulum (ER) stress, and …

Isoliquiritigenin (IsoLQ) is a flavonoid with antioxidant properties and inducer of
endoplasmic reticulum (ER) stress. In vitro and in vivo studies show that ER stress-mediated …

Oxidative stress and inflammation are considered to be the main pathogenesis of cisplatin
nephrotoxicity. Astilbin, a flavonoid with anti-oxidation and anti-inflammation function, has …

Cisplatin is a potent anti-cancer agent for various types of tumors. However, the clinical use
of cisplatin is often limited by its nephrotoxicity. This study reports that WZ tablet (WZ, a …

Cisplatin is a chemotherapeutant widely used in treating solid tumors, with the common side
effect of acute kidney injury (AKI). Developing effective useful agent for preventing or treating …

Cisplatin is an effective chemotherapeutic agent, but its clinical use is frequently limited by
its nephrotoxicity. The pathogenesis of cisplatin-induced acute kidney injury (AKI) remains …

Cisplatin, as an effective chemotherapeutic agent, is widely used to treat verious types of
cancers. Nephrotoxicity induced by cisplatin seriously limits its clinical application. Icariin, a …

Anti-cancer drugs such as cisplatin and doxorubicin are effectively used more than
radiotherapy. Cisplatin is a chemotherapeutic drug, used for treatment of various forms of …