Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis
DJ Stumpo, HE Broxmeyer, T Ward… - Blood, The Journal …, 2009 - ashpublications.org
Members of the tristetraprolin family of tandem CCCH finger proteins can bind to AU-rich
elements in the 3′-untranslated region of mRNAs, leading to their deadenylation and …
elements in the 3′-untranslated region of mRNAs, leading to their deadenylation and …
Chorioallantoic Fusion Defects and Embryonic Lethality Resulting from Disruption of Zfp36L1, a Gene Encoding a CCCH Tandem Zinc Finger Protein of the …
DJ Stumpo, NA Byrd, RS Phillips, S Ghosh… - … and cellular biology, 2004 - Taylor & Francis
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development
SBV Ramos, DJ Stumpo, EA Kennington, RS Phillips… - 2004 - journals.biologists.com
The CCCH tandem zinc finger protein, Zfp36l2, like its better-known relative tristetraprolin
(TTP), can decrease the stability of AU-rich element-containing transcripts in cell transfection …
(TTP), can decrease the stability of AU-rich element-containing transcripts in cell transfection …
Zfp36l3, a Rodent X Chromosome Gene Encoding a Placenta-Specific Member of the Tristetraprolin Family of CCCH Tandem Zinc Finger Proteins
PJ Blackshear, RS Phillips, S Ghosh… - Biology of …, 2005 - academic.oup.com
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger (TZF) proteins can
bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization …
bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization …
Phylogenetic distribution and evolution of the linked RNA-binding and NOT1-binding domains in the tristetraprolin family of tandem CCCH zinc finger proteins
PJ Blackshear, L Perera - Journal of Interferon & Cytokine Research, 2014 - liebertpub.com
In humans, the tristetraprolin or TTP family of CCCH tandem zinc finger (TZF) proteins
comprises 3 members, encoded by the genes ZFP36, ZFP36L1, and ZFP36L2. These …
comprises 3 members, encoded by the genes ZFP36, ZFP36L1, and ZFP36L2. These …
Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
RS Phillips, SBV Ramos, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts
WS Lai, JS Parker, SF Grissom, DJ Stumpo… - … and cellular biology, 2006 - Taylor & Francis
Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro∗
GA Taylor, MJ Thompson, WS Lai… - Journal of Biological …, 1995 - ASBMB
Tristetraprolin (TTP) is a potential transcription factor that contains three PPPPG repeats and
two putative CCCH zinc fingers. TTP is encoded by the early response gene Zfp-36, which is …
two putative CCCH zinc fingers. TTP is encoded by the early response gene Zfp-36, which is …
Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing …
WS Lai, EA Kennington, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Tristetraprolin (TTP), the prototype of a small family of CCCH tandem zinc finger (TZF)
domain proteins, is a physiological stimulator of instability of the mRNAs encoding tumor …
domain proteins, is a physiological stimulator of instability of the mRNAs encoding tumor …
Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover
PJ Blackshear - Biochemical Society Transactions, 2002 - portlandpress.com
The tristetraprolin (TTP) family of CCCH tandem zinc-finger proteins is composed of three
known members in mammals, with a fourth member recently identified in frogs and fish …
known members in mammals, with a fourth member recently identified in frogs and fish …