The Th17 pathway has recently been shown to play a critical role in host defense, allergic
responses and autoimmune inflammation. Th17 cells predominantly produce IL-17 and IL …

T helper 17 (Th17) cytokines are now widely believed to be critical for the regulation of
various chronic immune diseases. Investigations have revealed a significant role for IL-17 …

ABSTRACT IL-17 is a proinflammatory cytokine produced by immune cells. Its significance
in host defense and disease development has been demonstrated in various infection and …

Introduction: Asthma is a respiratory disorder typically characterized by T-helper type 2 (Th2)
inflammation that is mediated by cytokines, including IL-4, IL-5, and IL-13 …

Highlights•Th17 cells and cytokines are associated with the more severe phenotypes of
asthma.•IL-17A and IL-17F are associated with increased neutrophils in the airway.•IL-17A …

Steroid‐insensitive asthma is an infrequent but problematic airway disease that presents
with persistent symptoms, airflow limitation, or recurrent exacerbations even when treated …

Asthma is characterized by chronic airway inflammation with intense eosinophil and
lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness …

IL-17 cytokines are expressed by numerous cells (eg, gamma delta (γδ) T, innate lymphoid
(ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the …

Asthma is a major chronic disease ranging from mild to severe refractory disease and is
classified into various clinical phenotypes. Severe asthma is difficult to treat and frequently …

Asthma is the most prevalent allergic disease of the airway, which is characterized by
eosinophilic inflammation, mucus hyperproduction, and airway hyper-responsiveness …