RNA-binding protein tristetraprolin (TTP) plays a fundamental role in various physiological
and pathological processes including differentiation, reprogramming, metabolism …

The serine/threonine kinase Pim-1 directs selected signaling events that promote cell growth
and survival and is overexpressed in diverse human cancers. Pim-1 expression is tightly …

Current studies using knockout mice have revealed that some Cys–Cys–Cys–His (CCCH)-
type zinc-finger proteins, namely tristetraprolin (TTP), Roquin and Regnase-1, play important …

Meiosis is of prime importance for successful gametogenesis, and insufficient maintenance
of oocyte meiotic arrest compromises oocyte developmental competence. Recent studies …

Natriuretic peptide type C (NPPC) secreted by mural granulosa cells (MGCs) maintains
oocyte meiotic arrest via the activation of guanylyl cyclase-linked natriuretic peptide receptor …

Endometriosis, a major reproductive pathology affecting 8–10% of women is characterized
by chronic inflammation and immune dysfunction. Human antigen R (HuR) and …

The primordial follicle pool, providing all oocytes available to a female throughout her
reproductive life, is established perinatally. The formation of primordial follicle pool is …

Tristetraprolin (TTP), the best known member of a class of tandem (R/K) YKTELCX 8 CX 5
CX 3 H zinc finger proteins, can destabilize target mRNAs by first binding to AU-rich …

Tristetraprolin (TTP) is a regulator of TNF-α mRNA stability and is the only trans-acting factor
shown to be capable of regulating AU-rich element-dependent mRNA turnover at the level of …

Tristetraprolin (TTP), an mRNA binding and decaying protein, plays a significant role in
controlling inflammation by decaying mRNAs encoding inflammatory cytokines such as …