Members of the tristetraprolin (TTP/TIS11) family are important RNA-binding proteins initially
characterized as mediators of mRNA degradation. They act via their interaction with AU-rich …

Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of
reproductive age. Although much is understood concerning the pathology of PCOS, further …

Natriuretic peptide type C (NPPC) and its cognate receptor natriuretic peptide receptor 2
(NPR2) are essential for maintaining meiotic arrest in mouse oocytes residing in Graafian …

Tristetraprolin (TTP) is the only trans-acting factor shown to be capable of regulating AU-rich
element-dependent mRNA turnover at the level of the intact animal; however, the …

Oocyte meiosis is arrested at prophase I by factors secreted from surrounding somatic cells
after oocytes acquire meiotic competence at an early antral stage, and meiosis resumes in …

Tristetraprolin (TTP) is an acute phase protein, and its expression is rapidly up‐regulated by
inflammatory signals, such as lipopolysaccharide (LPS) and cytokines. TTP regulates gene …

Background Tristetraprolin (TTP) is a key mediator of processes such as inflammation
resolution, the inhibition of autoimmunity and in cancer. It carries out this role by the binding …

Members of the tristetraprolin (TTP) family of proteins participate in the regulation of mRNA
turnover after initially binding to AU-rich elements in target mRNAs. Related proteins from …

Recurrent spontaneous abortion (RSA) is a gestational disease with complex pathogenesis,
and trophoblast cells are closely involved in the pathogenesis of RSA. This study aimed to …

Tristetraprolin (TTP), the prototype member of the protein family of the same name, was
originally discovered as the product of a rapidly inducible gene in mouse cells. Development …