Safety, Immunogenicity, and Efficacy in Infancy of Oligosaccharide Conjugate Haemophilus influenzae Type b Vaccine in a United States Population: Possible …

SB Black, HR Shinefield, B Fireman… - Journal of Infectious …, 1992 - academic.oup.com
Abstract Between February 1988 and June 1990, the safety, immunogenicity, and efficacy of
Haemophilus influenzae type b (Hib) oligosaccharide conjugate (HbOC) vaccine was …

Efficacy in infancy of oligosaccharide conjugate Haemophilus influenzae type b (HbOC) vaccine in a United States population of 61 080 children

SB BLACK, HR SHINEFIELD, B Fireman… - The Pediatric …, 1991 - journals.lww.com
The efficacy of the HbOC conjugate Haemophilus influenzae type b vaccine was evaluated
in a study population of 61 080 infants in the Northern California Kaiser Permanente Medical …

Safety and immunogenicity of oligosaccharide conjugate Haemophilus influenzae type b (HbOC) vaccine in infancy

SB BLACK, HR SHINEFIELD… - The Pediatric …, 1991 - journals.lww.com
The safety and immunogenicity of the HbOC conjugate vaccine have been evaluated in a
study population of 61 080 children in the Kaiser Permanente Medical Care Program of …

Immunization with oligosaccharide conjugate Haemophilus influenzae type b (HbOC) vaccine on a large health maintenance organization population: extended follow …

SB Black, HR Shinefield - The Pediatric infectious disease journal, 1992 - europepmc.org
Between February, 1988, and June, 1990, the safety, immunogenicity and efficacy of the
HbOC (oligosaccharide conjugate Haemophilus influenza type b) vaccine was evaluated in …

Postlicensure surveillance for Haemophilus influenzae type b invasive disease after use of Haemophilus influenzae type b oligosaccharide CRM197 conjugate …

HR Shinefield, S Black - The Pediatric infectious disease journal, 1995 - journals.lww.com
Haemophilus influenzae type b (Hib) oligosaccharide CRM 197 (HbOC-HibTITER®, Lederle-
Praxis) conjugate vaccine was approved for use in infants in October, 1990, as a result of an …

Haemophilus influenzae type b vaccines: history, choice and comparisons

MD Decker, KM Edwards - The Pediatric infectious disease journal, 1998 - journals.lww.com
The conjugate Haemophilus influenzae type b (Hib) vaccines are safe and far more
immunogenic among infants and young children than is the unconjugated H. influenzae type …

Polysaccharide-protein conjugate vaccines for the prevention of Haemophilus influenzae type b disease

GA Weinberg, DM Granoff - The Journal of pediatrics, 1988 - Elsevier
In December 1987 the first Haemophilus influenzae type b polysaccharide-protein conjugate
vaccine was licensed for use in the United States., 2 The vaccine is composed of the Hib …

Response of 7-to 15-month-old infants to sequential immunization with Haemophilus influenzae type b-CRM197 conjugate and polysaccharide vaccines

EP Rothstein, RP Schiller, JAC Girone… - American Journal of …, 1991 - jamanetwork.com
• Objective.—To evaluate the immunologie potential of infants 7 to 15 months of age to
respond toHaemophilus influenzaetype b polysaccharide vaccine following immunization …

Protection provided by Haemophilus influenzae type b conjugate vaccines in Los Angeles County: a case-control study

CM Vadheim, DP Greenberg, E Eriksen… - The Pediatric …, 1994 - journals.lww.com
The objective was to assess the degree of disease control and to evaluate the protective
efficacy of licensed Haemophilus influenzae type b (Hib) conjugate vaccines (HbOC, PRP …

Three-Dose Vaccination of Infants Under 8 Months of Age with a Conjugate Haemophilus Influenzae Type B Vaccine

JE Rowe, IK Messinger, CA Schwendeman… - Military …, 1990 - academic.oup.com
The first licensed Haemophilus influenzae type B (Hib) vaccines were of a purified capsular
oligosaccharide. Unfortunately, oligosaccharides are poorly immunogenic in younger …