Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …

Many factors have been implicated in the pathophysiology of hypertension such as
upregulation of the renin-angiotensin-aldosterone system, activation of the sympathetic …

Increased vascular production of reactive oxygen species (ROS; termed oxidative stress)
has been implicated in various chronic diseases, including hypertension. Oxidative stress is …

Reactive oxygen species (ROS) are important signaling molecules in the vasculature.
However, when there is imbalance between their occurrence and antioxidant defense …

Hypertension is a major cardiovascular risk factor. Of the many processes involved in the
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …

Mammalian cells are capable of generating metabolites of oxygen, referred to as reactive
oxygen species (ROS) via the action of several enzymes. In vascular cells, ROS are …

Reactive oxygen species (ROS) are signaling molecules that influence many physiological
processes. Increased ROS bioavailability and altered redox signaling (oxidative stress) have …

Metabolism of oxygen by cells generates potentially deleterious reactive oxygen species
(ROS). Under normal conditions the rate and magnitude of oxidant formation is balanced by …

Reactive oxygen species (ROS), including superoxide (· O 2−), hydrogen peroxide (H 2 O 2),
and hydroxyl anion (OH-), and reactive nitrogen species, such as nitric oxide (NO) and …

A link between oxidative stress and hypertension has been firmly established in multiple
animal models of hypertension but remains elusive in humans. While initial studies focused …