Changes in outcomes and factors associated with survival in melanoma patients with brain metastases

M Hasanov, DR Milton, AB Davies, E Sirmans… - Neuro …, 2023 - academic.oup.com
Background Treatment options for patients with melanoma brain metastasis (MBM) have
changed significantly in the last decade. Few studies have evaluated changes in outcomes …

The impact of current treatment modalities on the outcomes of patients with melanoma brain metastases: a systematic review

MP van Opijnen, L Dirven… - … Journal of Cancer, 2020 - Wiley Online Library
Patients with melanoma brain metastases (MBM) still have a very poor prognosis. Several
treatment modalities have been investigated in an attempt to improve the management of …

The treatment of melanoma brain metastases before the advent of targeted therapies: associations between therapeutic choice, clinical symptoms and outcome with …

S Vecchio, F Spagnolo, DF Merlo, A Signori… - Melanoma …, 2014 - journals.lww.com
The management of melanoma brain metastases (MBM) includes different therapeutic
modalities, such as surgery, radiotherapy and chemotherapy. Despite the choice of …

Melanoma brain metastasis presentation, treatment, and outcomes in the age of targeted and immunotherapies

ED Bander, M Yuan, JA Carnevale, AS Reiner… - Cancer, 2021 - Wiley Online Library
Background Historically, the prognosis for patients who have melanoma brain metastasis
(MBM) has been dismal. However, breakthroughs in targeted and immunotherapies have …

[HTML][HTML] Systematic literature review and meta-analysis of clinical outcomes and prognostic factors for melanoma brain metastases

XL Tan, A Le, E Scherrer, H Tang, N Kiehl, J Han… - Frontiers in …, 2022 - frontiersin.org
Background More than 60% of all stage IV melanoma patients develop brain metastases,
while melanoma brain metastases (MBM) is historically difficult to treat with poor prognosis …

Survival and prognostic factors for patients with melanoma brain metastases in the era of modern systemic therapy

M Tio, X Wang, MS Carlino… - Pigment cell & …, 2018 - Wiley Online Library
Historically, the prognosis of patients with melanoma brain metastases is poor, with median
overall survival (OS) of 4‐6 months. Little is known of OS in the era of modern systemic …

Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma

TK Eigentler, A Figl, D Krex, P Mohr, C Mauch, K Rass… - Cancer, 2011 - Wiley Online Library
BACKGROUND: This multicenter study aimed to identify prognostic factors in patients with
brain metastases from malignant melanoma (BM‐MM). METHODS: In a retrospective survey …

[HTML][HTML] Impact of Novel Treatments in Patients with Melanoma Brain Metastasis: Real-World Data

SHAE Derks, JLM Jongen, EL van der Meer, LS Ho… - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous melanoma is highly prone to metastasize to the brain, with a
historically poor overall survival of only 4–5 months. Over the past decade, novel drugs such …

[HTML][HTML] Melanoma brain metastases in the era of targeted therapy and checkpoint inhibitor therapy

JM Rieth, U Swami, SL Mott, M Zanaty, MD Henry… - Cancers, 2021 - mdpi.com
Simple Summary Brain metastases are common in melanoma and are often associated with
significant morbidity and mortality. Although many new treatments for melanoma have been …

Clinical management of multiple melanoma brain metastases: a systematic review

S Goyal, AW Silk, S Tian, J Mehnert, S Danish… - JAMA …, 2015 - jamanetwork.com
Importance The treatment of multiple brain metastases (MBM) from melanoma is
controversial and includes surgical resection, stereotactic radiosurgery (SRS), and whole …