Immunomodulatory Role of Capsular Polysaccharides Constituents of Cryptococcus neoformans

D Decote-Ricardo, IF LaRocque-de-Freitas… - Frontiers in …, 2019 - frontiersin.org
Cryptococcosis is a systemic fungal infection caused by Cryptococcus neoformans. In
immunocompetent patients, cryptococcal infection is often confined to the lungs. In …

Phagocytosis of Cryptococcus neoformans by, and Nonlytic Exocytosis from, Acanthamoeba castellanii

CJ Chrisman, M Alvarez… - Applied and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans, an encapsulated, pathogenic yeast, is endowed with a variety of
virulence factors, including a polysaccharide capsule. During mammalian infection, the …

Cas1p is a membrane protein necessary for the O‐acetylation of the Cryptococcus neoformans capsular polysaccharide

G Janbon, U Himmelreich, F Moyrand… - Molecular …, 2001 - Wiley Online Library
The capsule is certainly the most obvious virulence factor for Cryptococcus neoformans. The
main capsule constituents are glucuronoxylomannans (GXM). Several studies have focused …

Immunoregulation by capsular components of Cryptococcus neoformans

A Vecchiarelli - Medical mycology, 2000 - academic.oup.com
Cryptococcus neoformans is an encapsulated yeast that is pathogenic for humans. The
capsule is a major virulence factor composed mainly of glucuronoxylomannan (GXM) and …

How Sweet it is! Cell Wall Biogenesis and Polysaccharide Capsule Formation in Cryptococcus neoformans

TL Doering - Annual review of microbiology, 2009 - annualreviews.org
Cryptococcus neoformans is a pathogenic fungus responsible for severe opportunistic
infections. The most prominent feature of this yeast is its elaborate polysaccharide capsule …

A novel protocol for the isolation of fungal extracellular vesicles reveals the participation of a putative scramblase in polysaccharide export and capsule construction in …

FCG Reis, BS Borges, LJ Jozefowicz, BAG Sena… - MSphere, 2019 - Am Soc Microbiol
Regular protocols for the isolation of fungal extracellular vesicles (EVs) are time-consuming,
hard to reproduce, and produce low yields. In an attempt to improve the protocols used for …

Elucidating the Immunological Function of the Cryptococcus Neoformans Capsule

A Vecchiarelli, E Pericolini, E Gabrielli… - Future …, 2013 - Taylor & Francis
The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent
of life-threatening infections in immunocompromised subjects. A unique characteristic of …

Cryptococcus neoformans Is a Facultative Intracellular Pathogen in Murine Pulmonary Infection

M Feldmesser, Y Kress, P Novikoff… - Infection and …, 2000 - Am Soc Microbiol
To produce chronic infection, microbial pathogens must escape host immune defenses.
Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic …

Intracellular parasitism of macrophages by Cryptococcus neoformans

M Feldmesser, S Tucker, A Casadevall - Trends in microbiology, 2001 - cell.com
Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …

Surface-Associated Plasminogen Binding of Cryptococcus neoformans Promotes Extracellular Matrix Invasion

J Stie, G Bruni, D Fox - PloS one, 2009 - journals.plos.org
Background The fungal pathogen Cryptococcus neoformans is a leading cause of illness
and death in persons with predisposing factors, including: malignancies, solid organ …