There is no agreement as to which variable best mirrors disease activity in rheumatoid
arthritis (RA) and no studies have been performed on the validity of disease activity …

An investigation of clinical and laboratory variables which might form the basis for judging
disease activity in clinical practice was made by six rheumatologists in a prospective study of …

In a prospective study of up to 3 years' duration of 113 patients with early rheumatoid arthritis
a disease activity score (DAS) was developed based on the clinical judgment of 6 …

Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …

We compared the sensitivity of several variables in 2 trials between second-line agents in
our clinic. In a trial comparing sulfasalazine with hydroxychloroquine significant differences …

Objective To determine the relative accuracy and sensitivity to change of 14 measures
commonly used to assess arthritis activity in patients with rheumatoid arthritis (RA). Methods …

Objectives To present the properties of an efficiency measure that may be used to make
statistical comparisons of sensitivities of trial outcome measures. To use this measure to …

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease with peripheral
synovitis as its main manifestation. The presentation of the disease and the course during …

There is no single 'gold standard'quantitative measure to assess and monitor the clinical
status in patients with rheumatoid arthritis (RA). Therefore, a variety of measures have been …

Health status measures are conceptually relevant to the assessment of clinical outcome in
the rheumatic diseases, but their ability to detect meaningful changes in health has not been …