Perspectives of long non-coding RNAs in cancer

AKDM Rao, T Rajkumar, S Mani - Molecular biology reports, 2017 - Springer
A recent advance in transcriptomics has spawned the 'Decade of non-coding RNAs' by
potentiating the growing numbers of long non-coding RNA in cancer. LncRNA involvement …

[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer

MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …

Molecular mechanisms of lncRNAs in the dependent regulation of cancer and their potential therapeutic use

C García-Padilla, Á Dueñas, V García-López… - International Journal of …, 2022 - mdpi.com
Deep whole genome and transcriptome sequencing have highlighted the importance of an
emerging class of non-coding RNA longer than 200 nucleotides (ie, long non-coding RNAs …

Long noncoding RNAs in cancer: mechanisms of action and technological advancements

N Bartonicek, JLV Maag, ME Dinger - Molecular cancer, 2016 - Springer
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …

Long noncoding RNAs in cancer and therapeutic potential

A Renganathan, E Felley-Bosco - Long Non Coding RNA Biology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are the major elements of the mammalian transcriptome
that is emerging as a central player controlling diverse cellular mechanisms. Most of the well …

Diagnostic, prognostic and therapeutic potential of long noncoding RNAs in cancer

MB Khawar, SE Hamid, T Jan, MH Abbasi… - Molecular Biology …, 2022 - Springer
Long noncoding RNAs (lncRNAs) are longer than 200 nucleotides in length and undergo
splicing, capping, polyadenylation, and editing just like mRNA. Evidence is growing that they …

[HTML][HTML] Long noncoding RNAs and their link to cancer

JM Grixti, D Ayers - Non-coding RNA research, 2020 - Elsevier
The central dogma of molecular biology, developed from the study of simple organisms such
as Escherichia coli, has up until recently been that RNA functions mainly as an information …

Investigating the structure and function of Long Non-Coding RNA (LncRNA) and its role in cancer

H Alsaedy, A Mirzaei, RA Alhashimi - Available at SSRN 4470175, 2023 - papers.ssrn.com
Cancer is one of the most complex and common diseases affected by many factors. In recent
years, many studies have been conducted on the genetic characteristics of cancer, among …

Long noncoding RNAs in cancer: from discovery to therapeutic targets

R Choudhari, MJ Sedano, AL Harrison… - Advances in clinical …, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …

Long non-coding RNAs: the regulatory mechanisms, research strategies, and future directions in cancers

N Gao, Y Li, J Li, Z Gao, Z Yang, Y Li, H Liu… - Frontiers in …, 2020 - frontiersin.org
The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …