[HTML][HTML] Stress-driven potentiation of lateral hypothalamic synapses onto ventral tegmental area dopamine neurons causes increased consumption of palatable food
LE Linders, L Patrikiou, M Soiza-Reilly… - Nature …, 2022 - nature.com
Stress can cause overconsumption of palatable high caloric food. Despite the important role
of stress eating in obesity and (binge) eating disorders, its underlying neural mechanisms …
of stress eating in obesity and (binge) eating disorders, its underlying neural mechanisms …
An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes
Maladaptation in balancing internal energy needs and external threat cues may result in
eating disorders. However, brain mechanisms underlying such maladaptations remain …
eating disorders. However, brain mechanisms underlying such maladaptations remain …
Diet-induced inflammation in the anterior paraventricular thalamus induces compulsive sucrose-seeking
Overconsumption of palatable food may initiate neuroadaptive responses in brain reward
circuitry that may contribute to eating disorders. Here we report that high-fat diet (HFD) …
circuitry that may contribute to eating disorders. Here we report that high-fat diet (HFD) …
Identification of a stress-sensitive anorexigenic neurocircuit from medial prefrontal cortex to lateral hypothalamus
Background A greater understanding of how the brain controls appetite is fundamental to
developing new approaches for treating diseases characterized by dysfunctional feeding …
developing new approaches for treating diseases characterized by dysfunctional feeding …
[HTML][HTML] Depression of accumbal to lateral hypothalamic synapses gates overeating
Overeating typically follows periods of energy deficit, but it is also sustained by highly
palatable foods, even without metabolic demand. Dopamine D1 receptor-expressing …
palatable foods, even without metabolic demand. Dopamine D1 receptor-expressing …
[HTML][HTML] Parallels and overlap: the integration of homeostatic signals by mesolimbic dopamine neurons
Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed,
animals and humans have fundamental drives to procure (appetitive behaviors) and …
animals and humans have fundamental drives to procure (appetitive behaviors) and …
[HTML][HTML] Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding
Hedonic feeding is driven by the “pleasure” derived from consuming palatable food and
occurs in the absence of metabolic need. It plays a critical role in the excessive feeding that …
occurs in the absence of metabolic need. It plays a critical role in the excessive feeding that …
Stress integration by an ascending adrenergic-melanocortin circuit
Stress is thought to be an important contributing factor for eating disorders; however, neural
substrates underlying the complex relationship between stress and appetite are not fully …
substrates underlying the complex relationship between stress and appetite are not fully …
Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids
The prevalence of obesity has markedly increased over the past few decades. Exploration of
how hunger and satiety signals influence the reward system can help us understand non …
how hunger and satiety signals influence the reward system can help us understand non …
Feelings about food: the ventral tegmental area in food reward and emotional eating
Overconsumption of high caloric food plays an important role in the etiology of obesity.
Several factors drive such hedonic feeding. High caloric food is often palatable. In addition …
Several factors drive such hedonic feeding. High caloric food is often palatable. In addition …