Prednisolone pharmacokinetics and pharmacodynamics in relation to sex and race

MH Magee, RA Blum, CD Lates… - The Journal of Clinical …, 2001 - Wiley Online Library
Prednisolone pharmacokinetics (PK) and pharmacyodynamics (PD) were investigated in
relation to sex and race in white males, black males, white females, and black females (n …

Evaluation of dose-related pharmacokinetics and pharmacodynamics of prednisolone in man

JA Wald, RM Law, EA Ludwig, RR Sloan… - … of pharmacokinetics and …, 1992 - Springer
The pharmacokinetics and pharmacodynamics of prednisolone were evaluated in normal
male volunteers. Seven subjects completed 3 phases: 16.4− and 49.2− mg iv prednisolone …

Gender‐based effects on methylprednisolone pharmacokinetics and pharmacodynamics

KH Lew, EA Ludwig, MA Milad… - Clinical …, 1993 - Wiley Online Library
The pharmacokinetics and selected pharmacodynamic responses to methylprednisolone
were investigated in six men and six premenopausal women after a dose of 0.6 mg/kg ideal …

Alterations in prednisolone disposition as a result of time of administration, gender and dose.

PJ Meffin, PM Brooks… - British journal of clinical …, 1984 - Wiley Online Library
The disposition of total and free prednisolone has been studied in four male and four female
volunteers, each of whom received an intravenous dose of 0.075 mg/kg (low) and 1.5 mg/kg …

Pharmacokinetics and pharmacodynamics of prednisolone after intravenous and oral administration.

J Barth, M Damoiseaux, H Möllmann… - … journal of clinical …, 1992 - europepmc.org
The pharmacokinetics and pharmacodynamics of prednisolone were investigated according
to four different routes of administration: 20 and 40 mg prednisolone orally in the morning …

Clinical pharmacokinetics of prednisone and prednisolone

BM Frey, FJ Frey - Clinical pharmacokinetics, 1990 - Springer
The growth of knowledge in the field of the pharmacokinetics of prednisolone/prednisone
has been slow for several reasons. First, convenient and specific methods for measuring …

Clinical pharmacokinetics of prednisone and prednisolone

ME Pickup - Clinical pharmacokinetics, 1979 - Springer
Prednisone and prednisolone are used in a wide variety of diseases. The two compounds
are metabolically interconvertible; prednisolone is assumed to be the pharmacologically …

Dose‐dependent prednisolone kinetics

A Tanner, F Bochner, J Caffin… - Clinical …, 1979 - Wiley Online Library
Kinetic data for prednisolone and prednisone have been determined following oral
administration of prednisolone over a dosage range of 5 to 200 mg in 43 subjects …

Dose equivalency evaluation of major corticosteroids: pharmacokinetics and cell trafficking and cortisol dynamics

DE Mager, SX Lin, RA Blum, CD Lates… - The Journal of …, 2003 - Wiley Online Library
The integrity of current corticosteroid dose equivalency tables, as assessed by mechanistic
models for cell trafficking and cortisol dynamics, was investigated in this study. Single …

Receptor‐based pharmacokinetic‐pharmacodynamic analysis of corticosteroids

H Derendorf, G Hochhaus, H Mölimann… - The Journal of …, 1993 - Wiley Online Library
The pharmacodynamics of three corticosteroids were investigated after intravenous
administration of the phosphate esters of methylprednisolone, dexamethasone, and …