Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Genetic variants associated with hyperandrogenemia in PCOS pathophysiology

R Dadachanji, N Shaikh… - Genetics research …, 2018 - Wiley Online Library
Polycystic ovary syndrome is a multifactorial endocrine disorder whose pathophysiology
baffles many researchers till today. This syndrome is typically characterized by anovulatory …

Polycystic ovary syndrome

R Azziz - Obstetrics & Gynecology, 2018 - journals.lww.com
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder, representing the single
most common endocrine–metabolic disorder in reproductive-aged women. Currently there …

[HTML][HTML] Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

F Day, T Karaderi, MR Jones, C Meun, C He… - PLoS …, 2018 - journals.plos.org
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism,
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …

Genetic basis of polycystic ovary syndrome

TM Barber, S Franks - Expert Review of Endocrinology & …, 2010 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is associated with obesity and manifests with
reproductive, hyperandrogenic and metabolic features. Although the etiology of PCOS is …

Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome

R Hart, M Hickey, S Franks - Best Practice & Research Clinical Obstetrics & …, 2004 - Elsevier
Polycystic ovarian morphology is seen on ultrasound in approximately 22% of women.
Polycystic ovary syndrome (PCOS) is a common and perplexing endocrine disorder of …

[PDF][PDF] Phenotype and genotype in polycystic ovary syndrome

RS Legro, R Spielman, M Urbanek… - … Prog Horm Res, 1998 - ndl.ethernet.edu.et
Polycystic ovary syndrome (PCOS) is the most common but least understood
endocrinopathy. Although a major genetic contribution is suspected, there have been no …

[HTML][HTML] Identifying genes associated with the development of human polycystic ovary syndrome

SY Saddick - Saudi Journal of Biological Sciences, 2020 - Elsevier
The pathophysiology of polycystic ovary syndrome (PCOS) is confusing until today as it is a
multifactorial endocrine disorder. It is presented with altered gonadotropin levels, bulky multi …

Criteria, phenotypes and prevalence of polycystic ovary syndrome.

LV Belenkaia, LM Lazareva, W Walker… - Minerva …, 2019 - europepmc.org
Polycystic ovarian syndrome (PCOS) is known as one of the most frequent endocrine
diseases in women worldwide. However, this term does not completely capture the diversity …

Hyperandrogenic origins of polycystic ovary syndrome–implications for pathophysiology and therapy

DH Abbott, DA Dumesic, JE Levine - Expert review of …, 2019 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) diagnosis comprises combinations of
female hyperandrogenism, menstrual irregularity and polycystic ovaries. While it is a familial …