G‐quadruplexes (G4) are four‐stranded structures formed from guanine‐rich
oligonucleotides. Their defined 3D structures and polymorphic nature set them apart from …

DNA is the chemotherapeutic target for treating diseases of genetic origin. Besides well-
known double-helical structures (A, B, Z, parallel stranded-DNA etc.), DNA is capable of …

Transition metal complexes allow fine tuning of DNA binding affinity and selectivity. Here we
report on the nucleic acid recognition properties of a phenanthroline-based ligand …

A G-rich sequence containing three loops to connect four G-tracts with each≥ 2 guanines
can possibly form G-quadruplex structures. Given that all G-quadruplex structures comprise …

The potential formation of G-quadruplexes in many regions of the genome makes them an
attractive target for drug design. A large number of small molecules synthesized in recent …

G-quadrplex DNA can exist in a rich variety of structural forms, ranging from unimolecular
folded structures containing diverse types of loops and strand oreintations, to bimolecular …

Despite a recent explosion of interest in G-quadruplex DNA, most fundamental questions
regarding the possible presence and function of these intriguing structures in vivo remain …

Four-stranded DNA structures formed by guanine-rich sequences are known as G-
quadruplexes. They have received much interest over the last decade owing to their …

G‐quadruplexes are special secondary structures adopted in some guanine‐rich DNA
sequences. As guanine‐rich sequences are present in important regions of the eukaryotic …

Because various non-parallel G-quadruplexes of human telomeric sequences in K+ solution
can be converted to a parallel G-quadruplex by adding polyethylene glycol (PEG) as a co …