[HTML][HTML] Comorbidities predict inferior survival in patients receiving chimeric antigen receptor T cell therapy for diffuse large B cell lymphoma: a multicenter analysis

AS Kittai, Y Huang, M Gordon, N Denlinger… - … and Cellular Therapy, 2021 - Elsevier
Chimeric antigen receptor T cell (CAR-T) therapy is approved for treatment of
relapsed/refractory (R/R) diffuse large B cell lymphoma (DLBCL). Here we evaluate whether …

[HTML][HTML] The International Prognostic Index is associated with outcomes in diffuse large B cell lymphoma after chimeric antigen receptor T cell therapy

M Garcia-Recio, K Wudhikarn, M Pennisi… - … and cellular therapy, 2021 - Elsevier
ABSTRACT CD19-targeted chimeric antigen receptor (CAR) T cells have shown excellent
activity against relapsed and refractory (R/R) diffuse large B cell lymphoma (DLBCL). CAR T …

A validated composite comorbidity index predicts outcomes of CAR T-cell therapy in patients with diffuse large B-cell lymphoma

G Shouse, A Kaempf, MJ Gordon, A Artz… - Blood …, 2023 - ashpublications.org
Chimeric antigen receptor T-cell therapy (CART) has extended survival of patients with
relapsed/refractory diffuse large B-cell lymphoma (DLBCL). However, limited durability of …

[HTML][HTML] Overcoming barriers to referral for chimeric antigen receptor T cell therapy in patients with relapsed/refractory diffuse large B cell lymphoma

MS Hoffmann, BD Hunter, PW Cobb, JC Varela… - … and Cellular Therapy, 2023 - Elsevier
Diffuse large B cell lymphoma (DLBCL) is the most prevalent subtype of non-Hodgkin
lymphoma. Although outcomes to frontline therapy are encouraging, patients who are …

Chimeric antigen receptor T‐cell therapy combined with autologous stem cell transplantation improved progression‐free survival of relapsed or refractory diffuse large …

T Wang, L Xu, L Gao, G Tang, L Chen… - Hematological …, 2022 - Wiley Online Library
Autologous hematopoietic stem cell transplantation (ASCT) and chimeric antigen receptor T‐
cell therapy (CART) are salvage therapies that are utilised for treatment of relapsed or …

Predictive factors of early progression after CAR T-cell therapy in relapsed/refractory diffuse large B-cell lymphoma

L Vercellino, R Di Blasi, S Kanoun, B Tessoulin… - Blood …, 2020 - ashpublications.org
Chimeric antigen receptor (CAR) T-cell therapy has emerged as an option for
relapsed/refractory aggressive B-cell lymphomas that have failed 2 lines of therapy. Failures …

Efficacy of chimeric antigen receptor T cell therapy and autologous stem cell transplant in relapsed or refractory diffuse large B-cell lymphoma: A systematic review

L Tian, C Li, J Sun, Y Zhai, J Wang, S Liu… - Frontiers in …, 2023 - frontiersin.org
Background We aimed to compare the efficacy of chimeric antigen receptor T (CAR-T) cell
therapy with that of autologous stem cell transplantation (auto-HSCT) in relapsed/refractory …

Relapsed/refractory diffuse large B-cell lymphoma patients. A multicenter retrospective analysis of eligibility criteria for car-T cell therapy

A Di Rocco, A Cuneo, A Di Rocco, F Merli… - Leukemia & …, 2021 - Taylor & Francis
Anti-CD19 chimeric antigen receptor (CAR) T cells represent the first approved third-line
therapy associated with long-term remissions in patients with refractory/relapsed (R/R) …

Efficacy and safety of second-generation CAR T-cell therapy in diffuse large B-cell lymphoma: a meta-analysis

M Al-Mansour, M Al-Foheidi… - Molecular and …, 2020 - spandidos-publications.com
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's
lymphoma (NHL), representing 30% of all lymphoma cases. Within the first 2-3 years …

Outcomes in patients with DLBCL treated with commercial CAR T cells compared with alternate therapies

D Sermer, C Batlevi, ML Palomba, G Shah… - Blood …, 2020 - ashpublications.org
The prognosis of patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma
(DLBCL) is poor. Chimeric antigen receptor (CAR) T-cell therapy has been approved for R/R …