Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma

H Hammad, BN Lambrecht - Nature Reviews Immunology, 2008 - nature.com
Dendritic cells (DCs) are generally held responsible for initiating and maintaining allergic T
helper 2 (TH2)-cell responses to inhaled allergens in asthma. Although the epithelium was …

Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

H Hammad, BN Lambrecht - Allergy, 2011 - Wiley Online Library
To cite this article: Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at
the interface between innate and adaptive immune responses. Allergy 2011; 66: 579–587 …

Dendritic cells in asthma

MJ van Helden, BN Lambrecht - Current opinion in immunology, 2013 - Elsevier
Highlights•Dendritic cells (DCs) are essential for inducing Th2 immunity to several
allergens.•Similar to other organs, lung DCs are a heterogeneous population of …

Dendritic cells in asthma: a function beyond sensitization

LS Van Rijt, BN Lambrecht - Clinical & Experimental Allergy, 2005 - Wiley Online Library
Allergic asthma is one of the most common chronic diseases in western society,
characterized by variable airway obstruction, mucus hypersecretion and infiltration of the …

The interplay of dendritic cells, Th2 cells and regulatory T cells in asthma

H Kuipers, BN Lambrecht - Current opinion in immunology, 2004 - Elsevier
Dendritic cells are essential for Th2 differentiation of naïve CD4+ T cells in response to
aeroallergens, and in recent years it has been well established that these cells play a pivotal …

[PDF][PDF] Biology of lung dendritic cells at the origin of asthma

BN Lambrecht, H Hammad - Immunity, 2009 - cell.com
Dendritic cells (DCs) initiate and maintain adaptive T helper 2 (Th2) cell responses to
inhaled allergens in asthma. Various functions like antigen uptake, migration to the draining …

[HTML][HTML] Dendritic cells: critical regulators of allergic asthma

I Morianos, M Semitekolou - International journal of molecular sciences, 2020 - mdpi.com
Allergic asthma is a chronic inflammatory disease of the airways characterized by airway
hyperresponsiveness (AHR), chronic airway inflammation, and excessive T helper (Th) type …

The role of dendritic cells in asthma

MA Gill - Journal of Allergy and Clinical Immunology, 2012 - Elsevier
Dendritic cells (DCs) are known to play a central role in sensing the presence of foreign
antigens and infectious agents and in initiating appropriate immune responses. More …

The role of dendritic and epithelial cells as master regulators of allergic airway inflammation

BN Lambrecht, H Hammad - The Lancet, 2010 - thelancet.com
Lung dendritic cells bridge innate and adaptive immunity, integrating a variety of stimuli from
allergens, microbial colonisation, environmental pollution, and innate immune cells into a …

Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation

H Hammad, BN Lambrecht - Journal of allergy and clinical immunology, 2006 - Elsevier
Dendritic cells (DCs) are crucial in determining the outcome of antigen encounter and
integrating signals derived from the antigen, its inflammatory context, and the host …