Fibrinogen is an abundant plasma protein that, when converted to fibrin by thrombin,
provides the main building blocks for the clot. Dys‐, a‐, and hypo‐fibrinogenemias have …

OBJECTIVE: Altered fibrin clot properties have been reported in cardiovascular diseases
(CVD) and inflammatory states. Given increased prevalence of CVD in patients with …

Fibrin formed from fibrinogen is the main component of thrombi. Clot structure is
characterized by fiber thickness and pore size, which differs within a given clot and between …

The formation of a fibrin clot is one of the key events in atherothrombotic vascular disease.
The structure of the fibrin clot and the genetic and environmental factors that modify it have …

Increased risk of thrombotic events occurs in chronic obstructive pulmonary disease
(COPD). Elevated fibrinogen and C-reactive protein (CRP), being common in COPD, are …

The central component of a blood clot is a network of fibrin fibres with which platelets and
blood cells interact. The structure of this fibrin network is an important regulator of …

Fibrin plays an essential role in hemostasis as both the primary product of the coagulation
cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly …

These findings defined mechanisms that control fibrin clot structure, strength and stability.
This basic information provides direction for clinical studies to examine clot properties in …

Objective—Hypofibrinolysis promotes atherosclerosis progression and recurrent ischemic
events in premature coronary artery disease. We investigated the role of fibrin physical …

BACKGROUND: Stable angina is associated with unfavorable fibrin structure/function. It is
not known how acute coronary syndromes (ACS) affect fibrin architecture. OBJECTIVE: We …