Common variation in the C-terminal region of the fibrinogen β-chain: effects on fibrin structure, fibrinolysis and clot rigidity
R Ajjan, BCB Lim, KF Standeven… - Blood, The Journal …, 2008 - ashpublications.org
Fibrinogen BβArg448Lys is a common polymorphism, positioned within the carboxyl
terminus of the Bβ-chain of the molecule. Studies suggest that it is associated with severity of …
terminus of the Bβ-chain of the molecule. Studies suggest that it is associated with severity of …
Abnormal fibrin clot architecture in nephrotic patients is related to hypofibrinolysis: influence of plasma biochemical modifications
JP Collet, Z Mishal, C Lesty, M Mirshahi… - Thrombosis and …, 1999 - thieme-connect.com
Porosity, viscoelasticity and morphological properties of plasma fibrin from 16 nephrotic
patients and 16 healthy volunteers were compared. Nephrotic patients were characterized …
patients and 16 healthy volunteers were compared. Nephrotic patients were characterized …
What is the biological and clinical relevance of fibrin?
RI Litvinov, JW Weisel - Seminars in thrombosis and …, 2016 - thieme-connect.com
As our knowledge of the structure and functions of fibrinogen and fibrin has increased
tremendously, several key findings have given some people a superficial impression that the …
tremendously, several key findings have given some people a superficial impression that the …
Fibrin (ogen) in cardiovascular disease: an update
W Koenig - Thrombosis and haemostasis, 2003 - thieme-connect.com
The notion that fibrinogen is strongly, consistently, and independently related to
cardiovascular risk has been widely accepted. The evidence is based on numerous …
cardiovascular risk has been widely accepted. The evidence is based on numerous …
Flow rate and fibrin fiber alignment
KC Gersh, KE Edmondson, JW Weisel - Journal of Thrombosis and …, 2010 - jthjournal.org
Fibrin clot structure strongly affects fibrinolysis rate and clot stability, and certain
characteristics have been correlated with premature myocardial infarction [1]. Consequently …
characteristics have been correlated with premature myocardial infarction [1]. Consequently …
Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice
Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia)
with risk of cardiovascular disease and arterial and venous thrombosis. However, it is …
with risk of cardiovascular disease and arterial and venous thrombosis. However, it is …
[HTML][HTML] Statins, fenofibrate, and quinapril increase clot permeability and enhance fibrinolysis in patients with coronary artery disease
A Undas, M Celinska‐Löwenhoff, T Löwenhoff… - Journal of Thrombosis …, 2006 - Elsevier
Background: Aspirin increases fibrin clot porosity and susceptibility to lysis. It is unknown
whether other drugs, in combination with aspirin, used in the treatment of coronary artery …
whether other drugs, in combination with aspirin, used in the treatment of coronary artery …
Coagulation and fibrinolysis in diabetes
SH Alzahrani, RA Ajjan - Diabetes and Vascular Disease …, 2010 - journals.sagepub.com
Atherothrombotic complications are the main cause of mortality in subjects with diabetes.
Premature atherosclerosis, increased platelet reactivity and activation of coagulation factors …
Premature atherosclerosis, increased platelet reactivity and activation of coagulation factors …
Changes in clot deformability—a possible explanation for the epidemiological association between plasma fibrinogen concentration and myocardial infarction
MC Scrutton, SB Ross-Murphy… - Blood coagulation & …, 1994 - journals.lww.com
This study examined the rheological properties of fibrin gels formed by adding thrombin to
plasma samples from 99 subjects with fibrinogen concentrations ranging from 1.45 to 4.14 …
plasma samples from 99 subjects with fibrinogen concentrations ranging from 1.45 to 4.14 …
Arterial thrombus formation in cardiovascular disease
The pathogenesis of arterial thrombosis is complex and dynamic. Unlike venous thrombi,
arterial thrombi typically form under conditions of high blood flow and are mainly composed …
arterial thrombi typically form under conditions of high blood flow and are mainly composed …