Fibrinogen BβArg448Lys is a common polymorphism, positioned within the carboxyl
terminus of the Bβ-chain of the molecule. Studies suggest that it is associated with severity of …

Porosity, viscoelasticity and morphological properties of plasma fibrin from 16 nephrotic
patients and 16 healthy volunteers were compared. Nephrotic patients were characterized …

As our knowledge of the structure and functions of fibrinogen and fibrin has increased
tremendously, several key findings have given some people a superficial impression that the …

The notion that fibrinogen is strongly, consistently, and independently related to
cardiovascular risk has been widely accepted. The evidence is based on numerous …

Fibrin clot structure strongly affects fibrinolysis rate and clot stability, and certain
characteristics have been correlated with premature myocardial infarction [1]. Consequently …

Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia)
with risk of cardiovascular disease and arterial and venous thrombosis. However, it is …

Background: Aspirin increases fibrin clot porosity and susceptibility to lysis. It is unknown
whether other drugs, in combination with aspirin, used in the treatment of coronary artery …

Atherothrombotic complications are the main cause of mortality in subjects with diabetes.
Premature atherosclerosis, increased platelet reactivity and activation of coagulation factors …

This study examined the rheological properties of fibrin gels formed by adding thrombin to
plasma samples from 99 subjects with fibrinogen concentrations ranging from 1.45 to 4.14 …

The pathogenesis of arterial thrombosis is complex and dynamic. Unlike venous thrombi,
arterial thrombi typically form under conditions of high blood flow and are mainly composed …