Association between Fetal MTHFR A1298C (rs1801131) Polymorphism and Neural Tube Defects Risk: A Systematic Review and Meta-Analysis

S Soleimani-Jadidi, B Meibodi, A Javaheri… - Fetal and Pediatric …, 2022 - Taylor & Francis
Background The association of the fetal MTHFR A1298C (rs1801131) polymorphism and
neural tube defects (NTDs) susceptibility has been widely demonstrated, but the results …

Association of fetal MTHFR C677T polymorphism with susceptibility to neural tube defects: a systematic review and update meta-analysis

RS Tabatabaei, N Fatahi-Meibodi… - Fetal and pediatric …, 2022 - Taylor & Francis
Background MTHFR gene may be a key epigenetic regulation-related factor crucial during
embryogenesis. We performed a meta-analysis to determine the association of fetal MTHFR …

Association between maternal MTHFR C677T polymorphism and neural tube defects in offsprings: a meta-analysis

Y Fang, S MA, O Shi, P Zhang… - Tianjin Medical Journal, 2015 - pesquisa.bvsalud.org
Objective To explore the association between maternal methylene tetrahydrofolate
reductase (MTHFR) C677T polymorphism and neural tube defects (NTDs). Methods CBM …

Association between maternal and fetal MTHFR C677T and mtrr A66G polymorphisms with the risk of ntds: a systematic review and meta-analysis study.

RM Jouibari, A Movafagh, A Molaei - 2021 - cabidigitallibrary.org
Abstract Background: Neural tube defects (NTDs) are classed as multifactorial birth defects
of the brain and spinal cord that arise during embryonic development. Although the etiology …

Association between MTHFR C677T polymorphism and neural tube defect risks: A comprehensive evaluation in three groups of NTD patients, mothers, and fathers

Y Yang, J Chen, B Wang, C Ding… - Birth Defects Research …, 2015 - Wiley Online Library
Background The C677T polymorphism in the methylenetetrahydrofolate reductase gene
(MTHFR) gene has been reported to play a critical role in the pathogenesis of neural tube …

Association of the Maternal MTHFR C677T Polymorphism with Susceptibility to Neural Tube Defects in Offsprings: Evidence from 25 Case-Control Studies

L Yan, L Zhao, Y Long, P Zou, G Ji, A Gu, P Zhao - 2012 - journals.plos.org
Background Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme in folate
metabolism and is involved in DNA methylation, DNA synthesis, and DNA repair. In addition …

MTHFD1 polymorphism as maternal risk for neural tube defects: a meta-analysis

J Zheng, X Lu, H Liu, P Zhao, K Li, L Li - Neurological Sciences, 2015 - Springer
Recently, the association between methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)
G1958A polymorphism and neural tube defects (NTD) susceptibility has been widely …

Association between MTHFR A1298C polymorphism and neural tube defect susceptibility: a metaanalysis

XW Wang, YL Luo, W Wang, Y Zhang, Q Chen… - American journal of …, 2012 - Elsevier
OBJECTIVE: To determine whether 5, 10-methylenetetrahydrofolate reductase A1298C
polymorphism is associated with neural tube defect susceptibility. STUDY DESIGN …

Meta-analysis on relationship between the Chinese maternal MTHFR gene polymorphism (C677T) and neural tube defects in offspring

C Zhang, J Huo, J Sun, J Huang, W Piao… - Wei sheng yan jiu …, 2018 - europepmc.org
Objective To explore the association between maternal MTHFR gene polymorphism
(C677T) and neural tube defects in offspring through Meta-analysis in China. Methods CNKI …

Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis

U Yadav, P Kumar, SK Yadav, OP Mishra, V Rai - Metabolic brain disease, 2015 - Springer
Epidemiological studies have evaluated the association between maternal
methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine synthase …