Novel 3‐alkoxymethyl/3‐phenyl indole‐2‐carboxamide derivatives were synthesized and
evaluated for their anticancer activity. Most of the tested compounds showed moderate to …

Based on the chemical structure of Pyrroloquinoline quinone (PQQ), a novel class of indole-
2-carboxylate derivatives was designed, synthesized and assayed for antiproliferative …

Three novel series of 2, 5‐disubstituted indole derivatives were synthesized and evaluated
in vitro for their antiproliferative activity against human cancer cells and HIV‐1 inhibition …

Abstract Reaction of 5-morphilinosulfonylisatin (1) with acetophenones (2a–e) afforded 3-
hydroxy-3-substituted-2-oxoindoles 3a-e, when treated with acetic acid the expected 3 …

The indole-3-carbinol (I3C) displays anti-cancer/proliferative activities against human cancer
cells. Cellular proliferation is an event associated with the progress and its continuation. This …

A small library of 2-indolinone derivatives with the 2, 6-dichlorophenyl ring at the N1 position
and with varying substitutions including aryl groups at the 3-position were synthesized, and …

α-Carboline (pyrido [2, 3-b] indole) was selected as the basic scaffold for development of
antileukemic agents by structural modification. From the structure-activity study, it was found …

Objective There is an urgent need drugs against particularly difficult to treat solid tumors
such as pancreatic, triple negative breast, lung, colon, metastatic prostate cancers and …

A series of novel 1-oxo-1, 2, 3, 4-tetrahydropyrazino [1, 2-a] indole-3-carboxamide analogs
were designed and synthesized for developing pyrazinoindolone scaffolds as anti-breast …

To prepare the anticancer indoles, a series of substituted heteroannulated indole derivatives
has been synthesized and characterized by spectral and elemental analysis. Subsequently …