Mouse kidney progenitor cells accelerate renal regeneration and prolong survival after ischemic injury

PT Lee, HH Lin, ST Jiang, PJ Lu, KJ Chou, HC Fang… - Stem …, 2010 - academic.oup.com
Acute tubular necrosis is followed by regeneration of damaged renal tubular epithelial cells,
and renal stem cells are supposed to contribute to this process. The purpose of our study is …

Isolation and characterization of kidney-derived stem cells

S Gupta, C Verfaillie, D Chmielewski… - Journal of the …, 2006 - journals.lww.com
Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells.
The purpose of this study was to test the hypothesis that renal stem cells exist in the adult …

[HTML][HTML] Progenitor-like cells derived from mouse kidney protect against renal fibrosis in a remnant kidney model via decreased endothelial mesenchymal transition

CL Chen, KJ Chou, HC Fang, CY Hsu… - Stem Cell Research & …, 2015 - Springer
Introduction Pathophysiological changes associated with chronic kidney disease impair
angiogenic processes and increase renal fibrosis. Progenitor-like cells derived from adult …

[HTML][HTML] Stem cells for kidney repair: useful tool for acute renal failure?

T Yokoo, T Kawamura, E Kobayashi - Kidney international, 2008 - Elsevier
Several cell types isolated from adult tissues have been reported to differentiate into mature
kidney cells that may participate in renal repair after systemic administration. Chen et al …

Kidney regeneration and resident stem cells

S Reule, S Gupta - Organogenesis, 2011 - Taylor & Francis
Given its complexity, high metabolic activity and excretory functions, the kidney is particularly
susceptible to acute ischemic and toxin-mediated injury. Current therapies do not facilitate …

Mesenchymal-like progenitors derived from human embryonic stem cells promote recovery from acute kidney injury via paracrine actions

J Luo, X Zhao, Z Tan, Z Su, F Meng, M Zhang - Cytotherapy, 2013 - Elsevier
Background aims The engraftment of mesenchymal stem cells (MSCs) is reported to
promote recovery of renal function in animal models of acute kidney injury (AKI). However, it …

Stem cells: potential and challenges for kidney repair

M Herrera, M Mirotsou - American Journal of Physiology …, 2014 - journals.physiology.org
Renal damage resulting from acute and chronic kidney injury poses an important problem to
public health. Currently, patients with end-stage renal disease rely solely on kidney …

Concise review: stem/progenitor cells for renal tissue repair: current knowledge and perspectives

S Aggarwal, A Moggio… - Stem Cells Translational …, 2013 - academic.oup.com
The kidney is a specialized low-regenerative organ with several different types of cellular
lineages; however, the identity of renal stem/progenitor cells with nephrogenic potential and …

Human kidney-derived cells ameliorate acute kidney injury without engrafting into renal tissue

I Santeramo, Z Herrera Perez, A Illera… - Stem Cells …, 2017 - academic.oup.com
Previous studies have suggested that CD133+ cells isolated from human kidney biopsies
have the potential to ameliorate injury following intravenous (IV) administration in rodent …

Label-retaining cells in the kidney: origin of regenerating cells after renal ischemia

A Maeshima - Clinical and experimental nephrology, 2007 - Springer
The kidney is capable of regeneration. In response to a variety of insults, renal epithelial
tubular cells dedifferentiate into an immature phenotype, proliferate, migrate to the injured …